Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | PGK2 | P07205 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.32 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | C1S | P09871 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741468 | 0.87 | ALDH1A1 (0.57) | ALDH1A1TSHRPGK1PGK2CYP11B1 | |
| SCHEMBL10823008 | 0.84 | PGK1 (0.37) | PGK1PGK2 | |
| SCHEMBL16953447 | 0.82 | ACHE (0.36) | PGK1PGK2IDH1ACHE | |
| SCHEMBL16954435 | 0.82 | TACR1 (0.40) | ALDH1A1PGK1PGK2TACR1 | |
| SCHEMBL4825346 | 0.82 | RAPGEF4 (0.33) | TSHRPGK1PGK2CNR1 | |
| SCHEMBL6130297 | 0.77 | ALDH1A1 (0.36) | ALDH1A1TSHRPGK1PGK2CYP11B1 | |
| SCHEMBL6742065 | 0.77 | CYP2A6 (0.38) | ALDH1A1IDH1 | |
| SCHEMBL9306852 | 0.75 | ALDH1A1 (0.61) | ALDH1A1TSHRACHETPMTPRSS1 | |
| SCHEMBL1145705 | 0.75 | ALDH1A1 (0.40) | ALDH1A1TSHRPGK1PGK2CYP11B1 | |
| SCHEMBL3690305 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TSHRPGK1PGK2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867706-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2021-05-28 | — | — | CN | claimed |
| EP-3802489-A2 | MASP-2 INHIBITORS AND METHODS OF USE | Omeros Corporation (US) | 2021-04-14 | — | — | EP | claimed |
| WO-2017199103-A1 | BENZAMIDE COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2017-11-23 | — | — | WO | claimed |
| CN-1932663-B | Electrophotographic image forming apparatus and process cartridge | RICOH KK | 2010-11-17 | — | — | CN | claimed |
| US-7304086-B2 | Inhibitors of glutaminyl cyclase | PROBIODRUG AG (DE) | 2007-12-04 | — | — | US | claimed |
| US-6620823-B2 | Antiinflammatory agents; rheumatic disorders | BRISTOL-MYERS SQUIBB PHARME COMPANY | 2003-09-16 | — | — | US | claimed |
| CN-117964684-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117964683-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2023101004-A1 | OLEFIN RESIN, METHOD FOR MANUFACTURING SAME, AND APPLICATION FOR SAME | 三井化学株式会社 | 2023-06-08 | — | — | WO | disclosed |
| US-20230145071-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION | 2023-05-11 | — | — | US | disclosed |
| US-11584714-B2 | MASP-2 inhibitors and methods of use | OMEROS CORPORATION (US) | 2023-02-21 | — | — | US | disclosed |
| CN-112867706-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2021-05-28 | — | — | CN | disclosed |
| EP-3802489-A2 | MASP-2 INHIBITORS AND METHODS OF USE | Omeros Corporation (US) | 2021-04-14 | — | — | EP | disclosed |
| EP-0284863-A2 | (Meth)acrylic-acid-ester-modified organic polysiloxanes, process for their preparation and their use as abhesive coatings | Th. Goldschmidt AG (DE) | 1988-10-05 | — | — | EP | disclosed |
| EP-0254799-A1 | (Meth)acrylic ester modified organopolysiloxanes, process for making them and their use as adhesive coating compositions | Th. Goldschmidt AG (DE) | 1988-02-03 | — | — | EP | disclosed |
| EP-0125020-A1 | Anti-treeing additives | DOW CORNING CORPORATION (US) | 1984-11-14 | — | — | EP | disclosed |
| EP-0109797-A2 | Polymeric compositions resistant to electrical and water treeing | DOW CORNING CORPORATION (US) | 1984-05-30 | — | — | EP | disclosed |
| US-4394505-A | ANTITUMOR AGENTS | SHIONOGI & CO., LTD. (JP) | 1983-07-19 | — | — | US | disclosed |
| EP-0064033-A1 | 5-Fluorouracil derivatives | SHIONOGI & CO., LTD. (JP) | 1982-11-03 | — | — | EP | disclosed |
| US-3997579-A | CATALYSTS FOR THE HYDROCYANATION OF ETHYLENE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11584714-B2 | MASP-2 inhibitors and methods of use | MASP2, METAP2, SPINT2 | ALDH1A1 4701/4885TSHR 3558/4885PGK1 3560/4885 |
| US-20230145071-A1 | MASP-2 INHIBITORS AND METHODS OF USE | MASP2, METAP2, SPINT2 | ALDH1A1 4701/4885TSHR 3558/4885PGK1 3560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.