Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643200 | 0.81 | OPRK1 (0.46) | KMT2AMEN1OPRK1POLBSMN1; SMN2 | |
| SCHEMBL17067423 | 0.80 | PKM (0.37) | KMT2AMEN1POLBTDP1GAA | |
| SCHEMBL15131216 | 0.75 | KDM4E (0.38) | KMT2ASMN1; SMN2CFDF11TPSB2 | |
| SCHEMBL17067369 | 0.75 | HDAC8 (0.41) | SMN1; SMN2TDP1GAAL3MBTL1LMNA | |
| SCHEMBL17067363 | 0.72 | RAB9A (0.34) | KMT2AMEN1SMN1; SMN2TDP1GAA | |
| SCHEMBL12305553 | 0.71 | LMNA (0.49) | KMT2AMEN1OPRK1POLBSMN1; SMN2 | |
| SCHEMBL24675205 | 0.71 | KDM4E (0.41) | SMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL15107044 | 0.71 | HDAC8 (0.44) | OPRK1POLBTDP1GAALMNA | |
| SCHEMBL12710451 | 0.70 | DUT (0.42) | KMT2ASMN1; SMN2CFDF11TPSB2 | |
| SCHEMBL12810290 | 0.70 | DUT (0.42) | KMT2ASMN1; SMN2CFDF11TPSB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2149561-B1 | TETRAHYDROISOQUINOLIN-1-ONE DERIVATIVE OR SALT THEREOF | SELDAR PHARMA INC (US) | 2015-09-09 | — | — | EP | disclosed |