Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | EED | O75530 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28127883 | 0.93 | ALDH1A1 (0.49) | ALDH1A1USP2LMNAKMT2AGPR84 | |
| SCHEMBL28779618 | 0.91 | RAB9A (0.48) | ALDH1A1USP2LMNAKMT2AGPR84 | |
| SCHEMBL5937271 | 0.88 | HTR6 (0.57) | ALDH1A1USP2LMNAKMT2AGPR84 | |
| Hydrochloric Acid SCHEMBL5705102 | 0.87 | SLC6A4 (0.57) | ALDH1A1USP2LMNAKMT2ASLC6A4 | |
| Hydrochloric Acid SCHEMBL30611185 | 0.87 | SLC6A4 (0.57) | ALDH1A1USP2LMNAKMT2ASLC6A4 | |
| SCHEMBL6663571 | 0.87 | LMNA (0.51) | ALDH1A1USP2LMNAKMT2AGPR84 | |
| SCHEMBL12534046 | 0.82 | LMNA (0.47) | ALDH1A1USP2LMNAKMT2AGPR84 | |
| SCHEMBL1890136 | 0.82 | HTR6 (0.50) | ALDH1A1USP2LMNAKMT2ASLC6A4 | |
| SCHEMBL5705162 | 0.82 | RORC (0.51) | ALDH1A1USP2LMNAKMT2AKDM4E | |
| SCHEMBL5937364 | 0.82 | ALDH1A1 (0.57) | ALDH1A1USP2LMNAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2915804-A1 | NOVEL AMINE DERIVATIVE OR SALT THEREOF | Toyama Chemical Co., Ltd. (JP) | 2015-09-09 | — | — | EP | disclosed |