Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29773623 | 0.69 | NCOA3 (0.48) | TOP2AMAPTRAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL29773613 | 0.69 | NCOA3 (0.48) | TOP2AMAPTRAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL10628276 | 0.68 | L3MBTL1 (0.64) | TOP2AMAPTRAB9AKDM4ELMNA | |
| SCHEMBL15677686 | 0.68 | MEN1 (0.57) | TOP2AMAPTPOLBKDM4ELMNA | |
| SCHEMBL10628263 | 0.66 | GAA (0.66) | TOP2AMAPTRAB9APOLBKDM4E | |
| SCHEMBL12683684 | 0.66 | GAA (0.53) | MAPTPOLBKDM4ELMNASMN1; SMN2 | |
| SCHEMBL28545385 | 0.65 | MAOB (0.67) | MAPTPOLBKDM4ELMNASMN1; SMN2 | |
| SCHEMBL20080903 | 0.65 | LMNA (0.61) | TOP2AMAPTRAB9APOLBKDM4E | |
| SCHEMBL18902030 | 0.65 | GRIN2D (0.36) | MAPTRAB9APOLBKDM4ECYP1A2 | |
| SCHEMBL15694788 | 0.64 | HTT (0.55) | MAPTRAB9APOLBKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2915806-A1 | NOVEL QUINOLINE COMPOUND AND USE THEREOF | Shenyang Pharmaceutical University (CN) | 2015-09-09 | — | — | EP | disclosed |