Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.32 |
| ▸ | CASP2 | P42575 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20420476 | 0.78 | LMNA (0.51) | TSHRALDH1A1LMNAPKMCNR1 | |
| SCHEMBL22015537 | 0.78 | CASP2 (0.50) | FAAHCASP2CNR1HPGDDNM1 | |
| SCHEMBL17229451 | 0.76 | ALDH1A1 (0.42) | TSHRALDH1A1LMNAPKMFAAH | |
| SCHEMBL22015478 | 0.75 | ALDH1A1 (0.41) | TSHRALDH1A1LPAR2LMNAPKM | |
| SCHEMBL17070318 | 0.73 | ALDH1A1 (0.35) | TSHRALDH1A1LMNAPKMFAAH | |
| SCHEMBL18911293 | 0.72 | HDAC3 (0.35) | — | |
| SCHEMBL20022932 | 0.71 | LMNA (0.44) | LPAR1TSHRALDH1A1LMNAPKM | |
| SCHEMBL19262105 | 0.70 | NOD1 (0.49) | — | |
| SCHEMBL21478093 | 0.68 | ALDH1A1 (0.43) | TSHRALDH1A1LMNAPKMFAAH | |
| SCHEMBL24535370 | 0.68 | CASP2 (0.42) | TSHRALDH1A1FAAHCASP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170152274-A1 | CHARGED LINKERS AND THEIR USES FOR CONJUGATION | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2017-06-01 | — | — | US | disclosed |
| US-20150250896-A1 | HYDROPHILIC LINKERS AND THEIR USES FOR CONJUGATION OF DRUGS TO A CELL BINDING MOLECULES | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2015-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152274-A1 | CHARGED LINKERS AND THEIR USES FOR CONJUGATION | PHOSPHO1, PCTP, CD2BP2 | LPAR1 249/4885TSHR 1807/4885ALDH1A1 4122/4885 |
| US-20150250896-A1 | HYDROPHILIC LINKERS AND THEIR USES FOR CONJUGATION OF DRUGS TO A CELL BINDING MOLECULES | CD44, EPCAM, ABCG2 | LPAR1 1833/4885TSHR 2204/4885ALDH1A1 1784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.