SCHEMBL17070923

SCHEMBL17070923

O=C1C(Cc2ccc(S(=O)(=O)O)cc2)C(=O)N2CCCCN12

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
ALDH1A1 P00352 7/20 0.35
TSHR P16473 4/20 0.35
NT5E P21589 1/20 0.35
MMP2 P08253 1/20 0.35
GAA P10253 3/20 0.35
EP300 Q09472 1/20 0.34
USP2 O75604 2/20 0.33
MAPT P10636 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MEN1 O00255 1/20 0.33
THRB P10828 1/20 0.33
RECQL P46063 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CES2 O00748 1/20 0.33
CMA1 P23946 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17070926 0.78 EP300 (0.54) LMNAALDH1A1TSHREP300SMN1; SMN2
SCHEMBL8763564 0.71 MEN1 (0.46) LMNAALDH1A1TSHRNT5EGAA
SCHEMBL15978125 0.71 HSD17B10 (0.41) LMNAALDH1A1TSHRNT5EGAA
SCHEMBL18328090 0.71 ALDH1A1 (0.34) LMNAALDH1A1MMP2GAAUSP2
SCHEMBL656154 0.70 KMT2A (0.44) LMNAALDH1A1TSHRNT5EGAA
SCHEMBL7100552 0.70 PTGS1 (0.51) LMNA
SCHEMBL658619 0.69 PTGS1 (0.38) LMNAALDH1A1TSHRNT5EGAA
SCHEMBL780173 0.69 LMNA (0.36) LMNAALDH1A1TSHRNT5EUSP2
SCHEMBL18328091 0.68 LMNA (0.41) LMNAALDH1A1TSHRMMP2GAA
SCHEMBL2275992 0.68 LMNA (0.42) LMNAALDH1A1TSHRNT5EMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160370523-A1 POLARIZING PLATE COMPOSITION, POLARIZING PLATE PROTECTIVE FILM, POLARIZER, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-22 US disclosed
US-9507067-B2 Polarizing plate and liquid crystal display device including the same FUJIFILM CORPORATION (JP) 2016-11-29 US disclosed
US-20160341860-A1 POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE INCLUDING SAME, AND METHOD FOR PRODUCING POLARIZING PLATE FUJIFILM CORPORATION (JP) 2016-11-24 US disclosed
US-20150253479-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE INCLUDING THE SAME FUJIFILM CORPORATION (JP) 2015-09-10 US disclosed