Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.54 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 6/20 | 0.41 |
| ▸ | BPTF | Q12830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 6/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17074608 | 0.80 | CNR2 (0.56) | CNR2CNR1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL17074610 | 0.78 | SMN1; SMN2 (0.57) | CNR2CNR1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL10366891 | 0.72 | SMN1; SMN2 (0.51) | CNR2CNR1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL17074609 | 0.72 | CNR2 (0.81) | CNR2CNR1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL17074602 | 0.71 | RAB9A (0.85) | CNR2CNR1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL17074595 | 0.70 | CNR2 (1.00) | CNR2CNR1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL17074594 | 0.70 | CNR2 (1.00) | CNR2CNR1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL9982691 | 0.70 | KDM4E (0.64) | CNR2CNR1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL17074605 | 0.69 | CNR2 (0.70) | CNR2CNR1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL3250048 | 0.69 | KAT2B (0.63) | CNR2BRD4BPTFKAT2BBRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2957560-A1 | PYRIDAZINE DERIVATIVES USEFUL AS CANNABINOID-2 AGONISTS | ALLERGAN, INC. (US) | 2015-12-23 | — | — | EP | disclosed |
| EP-2534137-B1 | PYRIDAZINE DERIVATIVES USEFUL AS CANNABINOID-2 AGONISTS | ALLERGAN INC (US) | 2015-09-16 | — | — | EP | disclosed |