SCHEMBL17075264

SCHEMBL17075264

C[C](ONC=O)ONC=O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1342561 0.79
Ammonia Solution, Strong SCHEMBL28640336 0.77
SCHEMBL11211880 0.77
SCHEMBL28860083 0.71
SCHEMBL163584 0.71
SCHEMBL28906986 0.69
SCHEMBL29478191 0.69 ALDH1A1 (0.36) ALDH1A1
SCHEMBL8587755 0.69
SCHEMBL11791161 0.68 ALDH1A1 (0.43) ALDH1A1
SCHEMBL11896621 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023230099-A1 COMPOSITIONS COMPRISING OLIGONUCLEOTIDE AND USES THEREOF SIRNAGEN THERAPEUTICS INCORPORATED (US) 2023-11-30 WO claimed
US-20210189398-A1 AMPHIREGULIN GENE-SPECIFIC DOUBLE-STRANDED OLIGONUCLEOTIDE AND COMPOSITION FOR PREVENTING AND TREATING FIBROSIS-RELATED DISEASES AND RESPIRATORY DISEASES, COMPRISING SAME BIONEER CORPORATION (KR) 2021-06-24 US claimed
US-20150259690-A1 AMPHIREGULIN-SPECIFIC DOUBLE-HELICAL OLIGO-RNA, DOUBLE-HELICAL OLIGO-RNA STRUCTURE COMPRISING DOUBLE-HELICAL OLIGO-RNA, AND COMPOSITION FOR PREVENTING OR TREATING RESPIRATORY DISEASES CONTAINING SAME BIONEER CORPORATION (KR) 2015-09-17 US claimed
WO-2023230099-A1 COMPOSITIONS COMPRISING OLIGONUCLEOTIDE AND USES THEREOF SIRNAGEN THERAPEUTICS INCORPORATED (US) 2023-11-30 WO disclosed
US-20220118093-A1 DOUBLE STRANDED OLIGONUCLEOTIDE CONSTRUCT COMPRISING ANDROGEN RECEPTOR SPECIFIC SEQUENCE, AND COMPOSITION FOR PREVENTING HAIR LOSS AND PROMOTING HAIR GROWTH COMPRISING SAME BIONEER CORPORATION (KR) 2022-04-21 US disclosed
US-20210299225-A1 COMPOSITION FOR TREATING OR SENSITIZING INTERFERON BETA RESISTANT CANCER DISEASE COMPRISING CFLIP SIRNA ABION INC. (KR) 2021-09-30 US disclosed
US-9695421-B2 Dengue virus-specific siRNA, double helix oligo-RNA structure comprising siRNA, and composition for suppressing proliferation of dengue virus comprising RNA structure BIONEER CORPORATION (KR) 2017-07-04 US disclosed
US-20170152512-A1 IMPROVED NANOPARTICLE TYPE OLIGONUCLEOTIDE STRUCTURE HAVING HIGH EFFICIENCY AND METHOD FOR PREPARING SAME BIONEER CORPORATION (KR) 2017-06-01 US disclosed
US-20150259690-A1 AMPHIREGULIN-SPECIFIC DOUBLE-HELICAL OLIGO-RNA, DOUBLE-HELICAL OLIGO-RNA STRUCTURE COMPRISING DOUBLE-HELICAL OLIGO-RNA, AND COMPOSITION FOR PREVENTING OR TREATING RESPIRATORY DISEASES CONTAINING SAME BIONEER CORPORATION (KR) 2015-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150259690-A1 AMPHIREGULIN-SPECIFIC DOUBLE-HELICAL OLIGO-RNA, DOUBLE-HELICAL OLIGO-RNA STRUCTURE COMPRISING DOUBLE-HELICAL OLIGO-RNA, AND COMPOSITION FOR PREVENTING OR TREATING RESPIRATORY DISEASES CONTAINING SAME AREG, OGFRL1, IGF2BP2 ALDH1A1 4711/4885
US-20170152512-A1 IMPROVED NANOPARTICLE TYPE OLIGONUCLEOTIDE STRUCTURE HAVING HIGH EFFICIENCY AND METHOD FOR PREPARING SAME PHAX, RPRD2, SMC2 ALDH1A1 4534/4885
US-20210189398-A1 AMPHIREGULIN GENE-SPECIFIC DOUBLE-STRANDED OLIGONUCLEOTIDE AND COMPOSITION FOR PREVENTING AND TREATING FIBROSIS-RELATED DISEASES AND RESPIRATORY DISEASES, COMPRISING SAME AREG, HDGF, MSTN ALDH1A1 4337/4885
US-20220118093-A1 DOUBLE STRANDED OLIGONUCLEOTIDE CONSTRUCT COMPRISING ANDROGEN RECEPTOR SPECIFIC SEQUENCE, AND COMPOSITION FOR PREVENTING HAIR LOSS AND PROMOTING HAIR GROWTH COMPRISING SAME AR, SHBG, NR5A1 ALDH1A1 3559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.