Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2321696 | 0.71 | HTR7 (0.38) | ADRA2AADRA2BADRA2CKDM4EMAPT | |
| SCHEMBL1147100 | 0.70 | CCR3 (0.71) | ACHECCR3BCHESIGMAR1KDM4E | |
| SCHEMBL7691593 | 0.69 | POLB (0.37) | — | |
| SCHEMBL6192806 | 0.69 | PNMT (0.37) | ADRA2AADRA2BADRA2C | |
| SCHEMBL27227657 | 0.68 | MBTD1 (0.53) | ACHESIGMAR1HRH3 | |
| SCHEMBL30658416 | 0.68 | MBTD1 (0.53) | ACHESIGMAR1HRH3 | |
| SCHEMBL31198934 | 0.68 | SIGMAR1 (0.75) | SIGMAR1KDM4EALDH1A1MAPTHTT | |
| SCHEMBL5871503 | 0.67 | MBTD1 (0.48) | ACHECCR3SIGMAR1ALDH1A1MAPT | |
| SCHEMBL26613393 | 0.67 | ESR1 (0.55) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL12450081 | 0.66 | PNMT (0.35) | ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3116504-A2 | RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | Innov17 LLC (US) | 2017-01-18 | — | — | EP | disclosed |
| WO-2015138276-A2 | RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | INNOV17 LLC (US) | 2015-09-17 | — | — | WO | disclosed |