Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5355347 | 0.79 | LMNA (0.61) | HSD17B10SMN1; SMN2LMNAELANEKMT2A | |
| SCHEMBL2785747 | 0.79 | HPGD (0.60) | HSD17B10SMN1; SMN2LMNAKMT2AMAPT | |
| SCHEMBL2787396 | 0.78 | FBP1 (0.43) | SMN1; SMN2KMT2AMAPTALDH1A1FBP1 | |
| SCHEMBL3422384 | 0.76 | ELANE (0.61) | HSD17B10SMN1; SMN2LMNAELANEKMT2A | |
| SCHEMBL2787935 | 0.74 | HPGD (0.42) | LMNAKMT2AALDH1A1GAAFBP1 | |
| SCHEMBL2784678 | 0.74 | RAB9A (0.48) | HSD17B10SMN1; SMN2KMT2AMAPTALDH1A1 | |
| SCHEMBL2787137 | 0.74 | HPGDS (0.51) | HSD17B10LMNAELANEKMT2AMAPT | |
| SCHEMBL12023642 | 0.73 | LMNA (0.53) | HSD17B10SMN1; SMN2LMNAELANEKMT2A | |
| SCHEMBL13047614 | 0.73 | LMNA (0.77) | HSD17B10SMN1; SMN2LMNAELANEKMT2A | |
| SCHEMBL6660837 | 0.72 | GAA (0.50) | HSD17B10SMN1; SMN2LMNAELANEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015137883-A1 | METHOD FOR PROTEIN CONJUGATION | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-09-17 | — | — | WO | disclosed |