Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565746 | 1.00 | MEN1 (0.43) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL17090516 | 0.88 | CRHR1 (0.47) | MEN1KMT2AALDH1A1LMNANPY5R | |
| SCHEMBL17090294 | 0.88 | LMNA (0.43) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL13564735 | 0.88 | LMNA (0.43) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL17090002 | 0.87 | KDM1A (0.40) | MEN1KMT2APOLBLMNANPY5R | |
| SCHEMBL17089949 | 0.86 | ALDH1A1 (0.50) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL13565755 | 0.86 | ALDH1A1 (0.50) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL17090528 | 0.86 | NPSR1 (0.36) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL13565324 | 0.86 | NPSR1 (0.36) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL13213210 | 0.86 | ALDH1A1 (0.39) | ALDH1A1NPY5RCRHR1CNR2ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |