Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13564937 | 1.00 | POLB (0.41) | POLBNR4A1RAB9AMAPTSMYD3 | |
| SCHEMBL13565755 | 0.89 | ALDH1A1 (0.50) | RAB9AMAPTCRHR1L3MBTL1ALDH1A1 | |
| SCHEMBL17089949 | 0.89 | ALDH1A1 (0.50) | RAB9AMAPTCRHR1L3MBTL1ALDH1A1 | |
| SCHEMBL17090294 | 0.89 | LMNA (0.43) | MAPTALDH1A1KDM4EMAPK14LMNA | |
| SCHEMBL13564735 | 0.89 | LMNA (0.43) | MAPTALDH1A1KDM4EMAPK14LMNA | |
| SCHEMBL17090367 | 0.86 | ALDH1A1 (0.48) | POLBL3MBTL1ALDH1A1MAPK14LMNA | |
| SCHEMBL13565155 | 0.86 | ALDH1A1 (0.48) | POLBL3MBTL1ALDH1A1MAPK14LMNA | |
| SCHEMBL17089962 | 0.85 | OPRD1 (0.43) | POLBCRHR1ALDH1A1KDM4ELMNA | |
| SCHEMBL13565514 | 0.85 | OPRD1 (0.43) | POLBCRHR1ALDH1A1KDM4ELMNA | |
| SCHEMBL13564974 | 0.84 | GRIA2 (0.58) | POLBNR4A1RAB9ASMYD3CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |