Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD5 | P21918 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1282300 | 0.83 | DRD1 (0.39) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL1699767 | 0.76 | DRD2 (0.40) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL10067643 | 0.69 | — | — | |
| SCHEMBL24308956 | 0.69 | ALDH1A1 (0.47) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL11837962 | 0.66 | RAB9A (0.47) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL10206109 | 0.62 | BCL2L1 (0.39) | DRD2DRD1DRD5DRD3 | |
| SCHEMBL1709095 | 0.60 | HSD17B10 (0.35) | DRD2DRD1 | |
| SCHEMBL1699765 | 0.60 | GPR84 (0.38) | — | |
| SCHEMBL11843579 | 0.59 | HTR2C (0.38) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL18329550 | 0.58 | L3MBTL1 (0.40) | DRD2DRD1DRD4DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088916-A1 | OCTAHYDRO BIQUINOLINE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-04-12 | — | — | US | disclosed |
| WO-2010132029-A1 | OCTAHYDRO BIQUINOLINE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2010-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088916-A1 | OCTAHYDRO BIQUINOLINE COMPOUND | CYP2S1, HCRTR2, CYP2B6 | DRD2 225/4885DRD1 406/4885DRD4 282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.