Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709367 | 0.88 | MEN1 (0.46) | SMN1; SMN2MEN1KMT2ATP53MDM2 | |
| SCHEMBL1709472 | 0.84 | DGAT1 (0.39) | SMN1; SMN2LMNAALDH1A1JAK2JAK1 | |
| SCHEMBL28171053 | 0.80 | L3MBTL1 (0.51) | L3MBTL1SMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL10032839 | 0.78 | KDM1A (0.40) | L3MBTL1JAK2JAK1TYK2JAK3 | |
| SCHEMBL1709417 | 0.77 | DPP4 (0.42) | L3MBTL1MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL6917416 | 0.76 | MDM2 (0.48) | SLC6A3TP53MDM2 | |
| SCHEMBL1709456 | 0.75 | ALDH1A1 (0.45) | SMN1; SMN2KMT2AALDH1A1TP53MDM2 | |
| SCHEMBL1709495 | 0.74 | MEN1 (0.38) | SMN1; SMN2MEN1KMT2ATP53MDM2 | |
| SCHEMBL6918303 | 0.73 | KDM1A (0.47) | SLC6A3 | |
| SCHEMBL13009584 | 0.73 | DGAT1 (0.42) | L3MBTL1LMNAHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |