Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709367 | 0.86 | MEN1 (0.46) | SMN1; SMN2 | |
| SCHEMBL1709360 | 0.84 | L3MBTL1 (0.43) | ALDH1A1SMN1; SMN2JAK2JAK1TYK2 | |
| SCHEMBL10032839 | 0.78 | KDM1A (0.40) | DGAT1MAOAJAK2JAK1TYK2 | |
| SCHEMBL1709504 | 0.76 | LMNA (0.40) | DGAT1MAOATDP1ALDH1A1ESR2 | |
| SCHEMBL13009578 | 0.76 | LMNA (0.40) | DGAT1MAOATDP1ALDH1A1ESR2 | |
| SCHEMBL13009584 | 0.75 | DGAT1 (0.42) | DGAT1MAOAALDH1A1MAPTCYP2C9 | |
| SCHEMBL13169131 | 0.75 | DGAT1 (0.42) | DGAT1MAOAALDH1A1MAPTCYP2C9 | |
| SCHEMBL13009593 | 0.75 | DGAT1 (0.42) | DGAT1MAOAALDH1A1MAPTCYP2C9 | |
| SCHEMBL1709456 | 0.75 | ALDH1A1 (0.45) | MAOAMAOBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL14113473 | 0.75 | DGAT1 (0.48) | DGAT1MAOAALDH1A1MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |