Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709384 | 0.91 | SIGMAR1 (0.40) | KMT2AMEN1HDAC6NPC1RAB9A | |
| SCHEMBL1709396 | 0.88 | ALDH1A1 (0.38) | HDAC6TDP1ALDH1A1 | |
| SCHEMBL1709393 | 0.83 | KDM4E (0.38) | HDAC6TDP1ALDH1A1 | |
| SCHEMBL1709395 | 0.80 | L3MBTL1 (0.39) | KMT2AMEN1HDAC6NPC1RAB9A | |
| SCHEMBL10033177 | 0.77 | GRIA4 (0.38) | HDAC6 | |
| SCHEMBL1709400 | 0.76 | TDP1 (0.39) | HDAC6HDAC3HDAC4HDAC1HDAC8 | |
| SCHEMBL1709374 | 0.71 | KMT2A (0.39) | KMT2AMEN1RAB9ATDP1ALDH1A1 | |
| SCHEMBL10033189 | 0.69 | TACR1 (0.39) | ALDH1A1 | |
| SCHEMBL1709416 | 0.69 | KDM1A (0.44) | HDAC6L3MBTL1 | |
| SCHEMBL10033104 | 0.69 | MEN1 (0.38) | KMT2AMEN1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |