Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709471 | 0.88 | KDM4E (0.40) | TDP1 | |
| SCHEMBL1709470 | 0.84 | KDM4E (0.40) | SLC6A2TDP1 | |
| SCHEMBL27763781 | 0.79 | ACHE (0.42) | — | |
| SCHEMBL5216002 | 0.71 | SLC6A3 (0.46) | SLC6A3SLC6A4SLC6A2TDP1 | |
| SCHEMBL5220468 | 0.71 | SLC6A3 (0.46) | SLC6A3SLC6A4SLC6A2TDP1 | |
| SCHEMBL5215996 | 0.71 | SLC6A3 (0.46) | SLC6A3SLC6A4SLC6A2TDP1 | |
| SCHEMBL1709493 | 0.70 | CYP2D6 (0.37) | MEN1KMT2A | |
| SCHEMBL13708996 | 0.68 | SCN9A (0.42) | SLC6A3 | |
| SCHEMBL2565281 | 0.68 | NPC1 (0.42) | OPRK1KMT2A | |
| SCHEMBL1709387 | 0.68 | SSTR3 (0.44) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |