Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.72 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | SRC | P12931 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3628018 | 0.82 | POLB (0.59) | AGTR1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL169758 | 0.80 | AGTR1 (0.48) | AGTR1P2RX4ABCB1PTGS2KMT2A | |
| SCHEMBL872109 | 0.79 | P2RX4 (0.81) | AGTR1P2RX4KMT2ALMNAMAPT | |
| SCHEMBL12611492 | 0.74 | P2RX4 (1.00) | AGTR1P2RX4KMT2ALMNAMAPT | |
| SCHEMBL170603 | 0.74 | ALDH1A1 (0.51) | AGTR1KMT2ALMNAMAPTHTT | |
| SCHEMBL6919741 | 0.72 | AGTR1 (0.55) | AGTR1P2RX4ABCB1PTGS2KMT2A | |
| SCHEMBL8515056 | 0.72 | AGTR1 (0.75) | AGTR1P2RX4PTGS2LMNAALDH1A1 | |
| SCHEMBL28810781 | 0.72 | LMNA (0.73) | AGTR1P2RX4ABCB1PTGS2KMT2A | |
| SCHEMBL1605381 | 0.71 | CYP11B2 (0.60) | AGTR1P2RX4ABCB1PTGS2LMNA | |
| SCHEMBL7980221 | 0.71 | SRC (0.87) | AGTR1P2RX4KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |