Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6471641 | 0.88 | POLB (0.45) | AGTR1P2RX4LMNAMAPTHTT | |
| SCHEMBL6922115 | 0.87 | ELANE (0.44) | AGTR1ABCB1P2RX4PTGS2LMNA | |
| SCHEMBL7128402 | 0.87 | PTGS2 (0.47) | AGTR1ABCB1PTGS2LMNAMAPT | |
| SCHEMBL6920262 | 0.85 | AGTR1 (0.39) | AGTR1ABCB1PTGS2MAPTHTT | |
| SCHEMBL6920229 | 0.85 | P2RX4 (0.47) | AGTR1ABCB1P2RX4PTGS2LMNA | |
| SCHEMBL6919743 | 0.77 | AGTR1 (0.53) | AGTR1ABCB1P2RX4PTGS2LMNA | |
| SCHEMBL6918965 | 0.74 | CYP19A1 (0.46) | P2RX4MAPTHTTALDH1A1HPGD | |
| SCHEMBL6440276 | 0.74 | POLB (0.49) | P2RX4LMNAMAPTHTTALDH1A1 | |
| SCHEMBL170977 | 0.72 | AGTR1 (0.72) | AGTR1ABCB1P2RX4PTGS2LMNA | |
| SCHEMBL6821009 | 0.68 | AGTR1 (0.46) | AGTR1PTGS2LMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |