Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8723823 | 0.81 | ACHE (0.42) | ACHECYP3A4TSHRKMT2AMEN1 | |
| SCHEMBL17904768 | 0.81 | ACHE (0.42) | ACHECYP3A4TSHRKMT2AMEN1 | |
| SCHEMBL19493387 | 0.81 | ACHE (0.42) | ACHECYP3A4TSHRKMT2AMEN1 | |
| SCHEMBL14701614 | 0.80 | ACHE (0.46) | ACHECYP3A4TSHRKMT2AMEN1 | |
| SCHEMBL104201 | 0.79 | ALDH1A3 (0.54) | ACHECYP3A4TSHRKMT2AMEN1 | |
| SCHEMBL1162019 | 0.79 | ACHE (0.50) | ACHECYP3A4TSHRKMT2AMEN1 | |
| SCHEMBL14704027 | 0.78 | ALDH1A1 (0.47) | ACHEKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL19833190 | 0.78 | ESR2 (0.46) | CYP3A4KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL14704047 | 0.78 | ALDH1A1 (0.47) | ACHEKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL13561319 | 0.78 | POLB (0.47) | CYP3A4ALDH1A1POLBLMNASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180030065-A1 | FLUORESCEIN POLYMER CONJUGATES | ISI LIFE SCIENCES, INC. (US) | 2018-02-01 | — | — | US | disclosed |
| US-20170196862-A2 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2017-07-13 | — | — | US | disclosed |
| EP-1521125-B1 | Electrophotographic photoconductor, electrophotographic method, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound | RICOH CO LTD (JP) | 2012-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180030065-A1 | FLUORESCEIN POLYMER CONJUGATES | PFAS, CD44, FGB | ACHE 4046/4885CYP3A4 1521/4885TSHR 2698/4885 |
| US-20170196862-A2 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1B, SLC26A4 | ACHE 4738/4885CYP3A4 3432/4885TSHR 1187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.