SCHEMBL1712597

SCHEMBL1712597

CCCCCCCCCCCCC(CCCCCCCC)(CCCCCCCCCC)C(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ NOD1 Q9Y239 4/20 0.52
▸ FOLH1 Q04609 6/20 0.49
▸ NAALAD2 Q9Y3Q0 2/20 0.49
▸ RIMKLA Q8IXN7 1/20 0.49
▸ PLA2G2C Q5R387 1/20 0.46
▸ PLA2G10 O15496 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.42
▸ TSHR P16473 1/20 0.42
▸ SLC22A6 Q4U2R8 1/20 0.42
▸ SLC22A8 Q8TCC7 1/20 0.42
▸ GPR84 Q9NQS5 1/20 0.42
▸ PPARG P37231 1/20 0.42
▸ PPARD Q03181 1/20 0.42
▸ PPARA Q07869 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1236115 0.87 NOD1 (0.49) NOD1FOLH1
SCHEMBL8431826 0.85 NOD1 (0.49) NOD1FOLH1NAALAD2RIMKLAPLA2G2C
Hydrochloric Acid SCHEMBL27396604 0.83 NOD1 (0.48) NOD1FOLH1NAALAD2RIMKLAPLA2G2C
SCHEMBL9954461 0.79 EPHX2 (0.46) NOD1GPR84
SCHEMBL28151788 0.79 NOD1 (0.68) NOD1PLA2G2CPLA2G10
SCHEMBL29811374 0.79 NOD1 (0.68) NOD1PLA2G2CPLA2G10
SCHEMBL28875772 0.79 NOD1 (0.48) NOD1FOLH1NAALAD2RIMKLAPLA2G2C
SCHEMBL10829302 0.78 NOD1 (0.82) NOD1FOLH1NAALAD2RIMKLAPLA2G2C
SCHEMBL9830302 0.78 NOD1 (0.82) NOD1FOLH1NAALAD2RIMKLAPLA2G2C
SCHEMBL17204092 0.78 NOD1 (0.82) NOD1FOLH1NAALAD2RIMKLAPLA2G2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8894981-B2 Water base slurry composition for cosmetic products and methods of use U.S. COSMETICS CORPORATION (US) 2014-11-25 — — US claimed
EP-2755628-A1 SPF ENHANCED EXTENDED COLOR BULK POWDERS AND METHODS OF MAKING THEREOF U.S. Cosmetics Corporation (US) 2014-07-23 — — EP claimed
EP-2727577-A1 Colour pigment powder, pigment dispersion and method of manufacture U.S. Cosmetics Corporation (US) 2014-05-07 — — EP claimed
WO-2013039483-A1 SPF ENHANCED EXTENDED COLOR BULK POWDERS AND METHODS OF MAKING THEREOF US COSMETICS CORPORATION (US) 2013-03-21 — — WO claimed
US-20120107379-A1 WATER BASE SLURRY COMPOSITION FOR COSMETIC PRODUCTS AND METHODS OF USE U.S. COSMETICS CORPORATION (US) 2012-05-03 — — US claimed
US-20110318286-A1 SPF ENHANCED EXTENDED COLOR BULK POWDERS AND METHODS OF MAKING THEREOF US COSMETICS CORPORATION (US) 2011-12-29 — — US claimed
EP-2344109-A2 WATER BASED SLURRY COMPOSITION CONTAINING SURFACE-TREATED COMPOSITE PARTICLES FOR COSMETIC PRODUCTS AND METHODS OF USE U.S. Cosmetics Corporation (US) 2011-07-20 — — EP claimed
EP-2148644-A2 COLOUR PIGMENT POWDER, PIGMENT DISPERSION AND METHOD OF MANUFACTURE U.S. Cosmetics Corporation (US) 2010-02-03 — — EP claimed
US-20090191139-A1 WATER BASE SLURRY COMPOSITION FOR COSMETIC PRODUCTS AND METHODS OF USE U.S. COSMETICS CORPORATION (US) 2009-07-30 — — US claimed
WO-2009067516-A2 WATER BASED SLURRY COMPOSITION FOR COSMETIC PRODUCTS AND METHODS OF USE US COSMETICS CORPORATION (US) 2009-05-28 — — WO claimed
US-20080299158-A1 FULLY EXTENDED COLOR BULK POWDER, BULK DISPERSION AND METHOD OF USE US COSMETICS CORPORATION (US) 2008-12-04 — — US claimed
WO-2008137175-A2 COLOUR PIGMENT POWDER, PIGMENT DISPERSION AND METHOD OF MANUFACTURE US COSMETICS CORPORATION (US) 2008-11-13 — — WO claimed
US-8894981-B2 Water base slurry composition for cosmetic products and methods of use U.S. COSMETICS CORPORATION (US) 2014-11-25 — — US disclosed
US-8894980-B2 Wet cake composition for cosmetic products and methods of use U.S. COSMETICS CORPORATION (US) 2014-11-25 — — US disclosed
EP-2755628-A1 SPF ENHANCED EXTENDED COLOR BULK POWDERS AND METHODS OF MAKING THEREOF U.S. Cosmetics Corporation (US) 2014-07-23 — — EP disclosed
EP-2727577-A1 Colour pigment powder, pigment dispersion and method of manufacture U.S. Cosmetics Corporation (US) 2014-05-07 — — EP disclosed
WO-2009067516-A2 WATER BASED SLURRY COMPOSITION FOR COSMETIC PRODUCTS AND METHODS OF USE US COSMETICS CORPORATION (US) 2009-05-28 — — WO disclosed
US-20080299158-A1 FULLY EXTENDED COLOR BULK POWDER, BULK DISPERSION AND METHOD OF USE US COSMETICS CORPORATION (US) 2008-12-04 — — US disclosed
WO-2008137175-A2 COLOUR PIGMENT POWDER, PIGMENT DISPERSION AND METHOD OF MANUFACTURE US COSMETICS CORPORATION (US) 2008-11-13 — — WO disclosed
EP-0869763-B1 SOLVENT-BASED NON-DRYING LIPSTICK OREAL (FR) 1999-09-29 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120107379-A1 WATER BASE SLURRY COMPOSITION FOR COSMETIC PRODUCTS AND METHODS OF USE DSG1, CUTA, AQP3 NOD1 4524/4885FOLH1 3643/4885NAALAD2 2840/4885
US-20090191139-A1 WATER BASE SLURRY COMPOSITION FOR COSMETIC PRODUCTS AND METHODS OF USE DSG1, CUTA, AQP3 NOD1 4524/4885FOLH1 3643/4885NAALAD2 2840/4885
US-20110318286-A1 SPF ENHANCED EXTENDED COLOR BULK POWDERS AND METHODS OF MAKING THEREOF SDHB, SDHA, SF3B3 NOD1 4077/4885FOLH1 3630/4885NAALAD2 4362/4885
US-20080299158-A1 FULLY EXTENDED COLOR BULK POWDER, BULK DISPERSION AND METHOD OF USE TYR, CUTA, PDE6D NOD1 4712/4885FOLH1 4383/4885NAALAD2 4508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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