SCHEMBL4580401

SCHEMBL4580401

Clc1ccc(Sc2cc[c]cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.56
MAOB P27338 3/20 0.56
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
CHRNA7 P36544 1/20 0.41
HAO1 Q9UJM8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
LMNA P02545 1/20 0.40
CYP2A6 P11509 1/20 0.40
MAPT P10636 3/20 0.39
NPC1 O15118 1/20 0.39
HTT P42858 1/20 0.39
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
RHEB Q15382 1/20 0.39
CYP3A4 P08684 3/20 0.38
KDM4E B2RXH2 2/20 0.38
CYP1A2 P05177 2/20 0.38
HPGD P15428 2/20 0.38
CYP2C19 P33261 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28432241 0.93 MAOA (0.50) MAOAMAOBMEN1KMT2ACHRNA7
SCHEMBL1712836 0.84 NR1H2 (0.40) MAOAMAOBL3MBTL1LMNACYP3A4
SCHEMBL9476350 0.84 MAOA (0.64) MAOAMAOBMEN1KMT2ACHRNA7
SCHEMBL9475224 0.84 MAOA (0.64) MAOAMAOBMEN1KMT2ACHRNA7
SCHEMBL481976 0.84 MAOA (0.64) MAOAMAOBMEN1KMT2ACHRNA7
SCHEMBL6546581 0.81 MAOA (0.61) MAOAMAOBMEN1KMT2ACHRNA7
SCHEMBL6546576 0.81 MAOA (0.61) MAOAMAOBMEN1KMT2ACHRNA7
SCHEMBL5687937 0.78 GRM5 (0.44) MAOAMAOBMEN1KMT2AHAO1
SCHEMBL13837350 0.77 NR1H2 (0.38) MAOAMAOBMEN1KMT2AL3MBTL1
SCHEMBL5023998 0.77 MAOA (0.54) MAOAMAOBCHRNA7MAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1298490-B1 Photopolymerizable composition and recording material FUJIFILM CORP (JP) 2008-08-13 EP disclosed
US-7399569-B2 Method for producing microcapsules, microcapsules, recording material, and heat-sensitive recording material FUJIFILM CORPORATION (JP) 2008-07-15 US disclosed
US-7220529-B2 Photopolymerizable composition and recording material using the same FUJIFILM CORPORATION (JP) 2007-05-22 US disclosed
US-7205083-B2 Recording material FUJIFILM CORPORATION (JP) 2007-04-17 US disclosed
US-20070047038-A1 Hologram recording method, hologram recording material, optical recording medium FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20070048666-A1 Two-photon recording method, two-photon absorption recording material, two-photon absorption recording-reproduction method and optical recoding medium FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
EP-1254780-B1 Recording material FUJI PHOTO FILM CO LTD (JP) 2007-01-03 EP disclosed
US-7157407-B2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2007-01-02 US disclosed
US-7094731-B2 Recording material FUJI PHOTO FILM CO., LTD. (JP) 2006-08-22 US disclosed
US-20060122064-A1 Amides and method for plant diseases control with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-06-08 US disclosed
EP-1035124-A1 Borate compound, and photopolymerizable composition and recording material which contain the same FUJI PHOTO FILM CO., LTD. (JP) 2000-09-13 EP disclosed
US-5925489-A CONTAINING DIAZONIUM SALT AND PYRROLOPYRIMIDINE COUPLER WHICH REACT WHEN HEATED TO DEVELOP VIOLET TO CYAN COLORS, IMAGE QUALITY AND STABILITY, SHELF LIFE FUJI PHOTO FILM CO., LTD. (JP) 1999-07-20 US disclosed
EP-0534257-B1 Salicylic acid derivatives, the process for preparing the same and the heat-sensitive recording materials comprising thereof MITSUI TOATSU CHEMICALS (JP) 1997-03-12 EP disclosed
EP-0524419-B1 Heat-sensitive recording materials and phenol compounds MITSUI TOATSU CHEMICALS (JP) 1995-09-06 EP disclosed
US-5391806-A A storage stable chromogens as color-developing agent or stabilizers MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-02-21 US disclosed
US-5306688-A Color-forming, electron donating compound and electron accepting compound; storage stability of uncolored portion MITSUI TOATSU CHEMICALS, INC. (JP) 1994-04-26 US disclosed
US-5270281-A Chromogenic compound MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1993-12-14 US disclosed
EP-0534257-A1 Salicylic acid derivatives, the process for preparing the same and the heat-sensitive recording materials comprising thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-31 EP disclosed
EP-0524419-A1 Heat-sensitive recording materials and phenol compounds MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-01-27 EP disclosed
US-4285961-A MICROBIOCIDES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1981-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122064-A1 Amides and method for plant diseases control with the same ARG1, ARGLU1, ARG2 MAOA 2114/4885MAOB 1610/4885MEN1 3091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.