Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1712836 | 0.84 | NR1H2 (0.40) | NR1H2CYP3A4TSHRMAPK1L3MBTL1 | |
| SCHEMBL576260 | 0.84 | MEN1 (0.48) | MEN1KMT2AMAPTCYP1A2CYP2C9 | |
| SCHEMBL28256971 | 0.78 | CA1 (0.42) | CA1CA2CA7CA9ACHE | |
| SCHEMBL5684842 | 0.78 | GRM5 (0.36) | NR1H2CYP3A4TSHRMAPK1MAOA | |
| SCHEMBL5023998 | 0.77 | MAOA (0.54) | MAPTNR1H2CYP3A4TSHRMAPK1 | |
| SCHEMBL13837350 | 0.77 | NR1H2 (0.38) | MEN1KMT2AMAPTNR1H2CYP3A4 | |
| SCHEMBL5685309 | 0.76 | HAO1 (0.45) | MAOAMAOBACHE | |
| SCHEMBL9686247 | 0.76 | MAOA (0.35) | MEN1KMT2AMAPTCYP1A2CYP2C9 | |
| SCHEMBL4115867 | 0.76 | MEN1 (0.44) | MEN1KMT2AMAPTCYP1A2CYP2C9 | |
| SCHEMBL3163844 | 0.75 | MLYCD (0.44) | MEN1KMT2AMAPTNR1H2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013110313-A1 | SELECTIVE ALLOSTERIC MODULATORS OF THE SEROTONIN TRANSPORTER | H. LUNDBECK A/S (DK) | 2013-08-01 | — | — | WO | claimed |
| WO-2013110313-A1 | SELECTIVE ALLOSTERIC MODULATORS OF THE SEROTONIN TRANSPORTER | H. LUNDBECK A/S (DK) | 2013-08-01 | — | — | WO | disclosed |
| WO-2013110313-A1 | SELECTIVE ALLOSTERIC MODULATORS OF THE SEROTONIN TRANSPORTER | H. LUNDBECK A/S (DK) | 2013-08-01 | — | — | WO | disclosed |
| US-20060122064-A1 | Amides and method for plant diseases control with the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-06-08 | — | — | US | disclosed |
| EP-1640360-A1 | AMIDES AND METHOD FOR PLANT DISEASE CONTROL WITH THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-03-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122064-A1 | Amides and method for plant diseases control with the same | ARG1, ARGLU1, ARG2 | MEN1 3091/4885KMT2A 1374/4885MAPT 3783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.