Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.50 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29480443 | 0.83 | CTSK (0.58) | PTPN1CTSKCTSSCTSLCTSB | |
| SCHEMBL17130698 | 0.82 | SYK (0.49) | — | |
| SCHEMBL17935598 | 0.82 | CASP3 (0.48) | PTPN1CASP3 | |
| SCHEMBL9449847 | 0.81 | CTSK (0.57) | PTPN1CTSKCTSSCTSLCTSB | |
| SCHEMBL25186508 | 0.79 | CASP3 (0.59) | PTPN1CASP3 | |
| SCHEMBL119197 | 0.79 | CASP3 (0.59) | PTPN1CASP3 | |
| SCHEMBL14265318 | 0.79 | CASP3 (0.59) | PTPN1CASP3 | |
| SCHEMBL29400907 | 0.79 | CASP3 (0.59) | PTPN1CASP3 | |
| SCHEMBL30759963 | 0.79 | CASP3 (0.59) | PTPN1CASP3 | |
| SCHEMBL9449865 | 0.79 | CASP3 (0.50) | PTPN1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170058002-A1 | GAMMA-AAPEPTIDES WITH POTENT AND BROAD-SPECTRUM ANTIMICROBIAL ACTIVITY | UNIVERSITY OF SOUTH FLORIDA (US) | 2017-03-02 | — | — | US | disclosed |
| US-9499587-B2 | Gamma-AApeptides with potent and broad-spectrum antimicrobial activity | UNIVERSITY OF SOUTH FLORIDA (US) | 2016-11-22 | — | — | US | disclosed |
| US-20150274782-A1 | GAMMA-AAPEPTIDES WITH POTENT AND BROAD-SPECTRUM ANTIMICROBIAL ACTIVITY | UNIVERSITY OF SOUTH FLORIDA (US) | 2015-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274782-A1 | GAMMA-AAPEPTIDES WITH POTENT AND BROAD-SPECTRUM ANTIMICROBIAL ACTIVITY | ANPEP, DNPEP, ENPEP | PTPN1 1020/4885PSMB1 1396/4885PSMB5 1765/4885 |
| US-20170058002-A1 | GAMMA-AAPEPTIDES WITH POTENT AND BROAD-SPECTRUM ANTIMICROBIAL ACTIVITY | ANPEP, DNPEP, ENPEP | PTPN1 1020/4885PSMB1 1396/4885PSMB5 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.