Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14457946 | 0.83 | NAAA (0.42) | NAAA | |
| SCHEMBL12432875 | 0.83 | TSHR (0.40) | TSHRNAAA | |
| SCHEMBL13111150 | 0.82 | — | — | |
| SCHEMBL5608131 | 0.82 | TSHR (0.44) | TSHRNAAADPP4 | |
| SCHEMBL1818541 | 0.81 | TSHR (0.39) | TSHRNAAA | |
| SCHEMBL13111151 | 0.79 | NPSR1 (0.32) | — | |
| SCHEMBL5176210 | 0.78 | TSHR (0.44) | TSHRNAAA | |
| SCHEMBL1817331 | 0.78 | TSHR (0.39) | TSHRDPP4 | |
| SCHEMBL13111173 | 0.77 | PRKCA (0.33) | DPP4 | |
| SCHEMBL10053101 | 0.76 | TSHR (0.40) | TSHRDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10195135-B2 | Organopolysiloxane graft polymer | KAO CORPORATION (JP) | 2019-02-05 | — | — | US | disclosed |
| EP-2927253-B1 | ORGANOPOLYSILOXANE GRAFT POLYMER | KAO CORP (JP) | 2018-09-12 | — | — | EP | disclosed |
| EP-2957581-B1 | ORGANOPOLYSILOXANE GRAFT POLYMER | KAO CORP (JP) | 2018-04-18 | — | — | EP | disclosed |
| US-9351920-B2 | Organopolysiloxane graft polymer | KAO CORPORATION (JP) | 2016-05-31 | — | — | US | disclosed |
| US-20150374612-A1 | ORGANOPOLYSILOXANE GRAFT POLYMER | KAO CORPORATION (JP) | 2015-12-31 | — | — | US | disclosed |
| EP-2957581-A1 | ORGANOPOLYSILOXANE GRAFT POLYMER | Kao Corporation (JP) | 2015-12-23 | — | — | EP | disclosed |
| US-20150297498-A1 | ORGANOPOLYSILOXANE GRAFT POLYMER | KAO CORPORATION (JP) | 2015-10-22 | — | — | US | disclosed |
| EP-2927253-A1 | ORGANOPOLYSILOXANE GRAFT POLYMER | Kao Corporation (JP) | 2015-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150374612-A1 | ORGANOPOLYSILOXANE GRAFT POLYMER | IDUA, PIGS, MPST | TSHR 3902/4885NAAA 2534/4885DPP4 2562/4885 |
| US-20150297498-A1 | ORGANOPOLYSILOXANE GRAFT POLYMER | IDUA, PIGS, GMNN | TSHR 2848/4885NAAA 3078/4885DPP4 3439/4885 |
| US-10195135-B2 | Organopolysiloxane graft polymer | IDUA, PIGS, MPST | TSHR 3902/4885NAAA 2534/4885DPP4 2562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.