SCHEMBL17138223

SCHEMBL17138223

Cc1cc(C)c(N(c2ccc(-c3ccccc3)cc2)c2cccc(-c3cccc(N(c4ccc(-c5ccccc5)cc4)c4c(C)cc(C)cc4C)c3)c2)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS2 Q9H2K2 1/20 0.37
PSMB5 P28074 1/20 0.37
HSD17B1 P14061 2/20 0.37
HSD17B2 P37059 2/20 0.37
NPC1 O15118 1/20 0.35
MGLL Q99685 1/20 0.34
MAPT P10636 2/20 0.34
ALDH1A1 P00352 2/20 0.34
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
KDM4E B2RXH2 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ACMSD Q8TDX5 1/20 0.33
BACE1 P56817 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8739832 0.93 HSD17B1 (0.39) TNKS2PSMB5HSD17B1HSD17B2MAPT
SCHEMBL16344198 0.91 PSMB5 (0.42) TNKS2PSMB5MGLLMAPTALDH1A1
SCHEMBL9244552 0.91 ALDH1A1 (0.39) PSMB5MAPTALDH1A1LMNASMN1; SMN2
SCHEMBL19241177 0.88 MEN1 (0.40) PSMB5NPC1MAPTALDH1A1LMNA
SCHEMBL17528629 0.87 PSMB5 (0.37) TNKS2PSMB5NPC1MAPTALDH1A1
SCHEMBL15679738 0.87 PSMB5 (0.37) TNKS2PSMB5HSD17B1HSD17B2NPC1
SCHEMBL17138224 0.86 PSMB5 (0.39) TNKS2PSMB5HSD17B1HSD17B2ALDH1A1
SCHEMBL13104649 0.86 PSMB5 (0.36) TNKS2PSMB5NPC1MAPTALDH1A1
SCHEMBL1115692 0.86 L3MBTL1 (0.43) PSMB5MAPTALDH1A1LMNASMN1; SMN2
SCHEMBL19998836 0.85 CYP1A2 (0.42) TNKS2HSD17B1HSD17B2MGLLMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4734717-A1 DISPLAY COMPRISING AN ORGANIC PHOTODETECTOR AND AN ORGANIC LIGHT EMITTING DEVICE Novaled GmbH (DE) 2026-04-29 EP disclosed
EP-4734719-A1 DISPLAY COMPRISING AN ORGANIC PHOTODETECTOR AND AN ORGANIC LIGHT EMITTING DEVICE Novaled GmbH (DE) 2026-04-29 EP disclosed
EP-4646073-A1 ORGANIC PHOTODETECTOR, ORGANIC ELECTRONIC DEVICE COMPRISING THE ORGANIC PHOTOTECTOR AS WELL AS A DISPLAY DEVICE COMPRISING THE ORGANIC ELECTRONIC DEVICE Novaled GmbH (DE) 2025-11-05 EP disclosed
EP-4646074-A1 ORGANIC PHOTODETECTOR, ORGANIC ELECTRONIC DEVICE COMPRISING THE ORGANIC PHOTOTECTOR AS WELL AS A DISPLAY DEVICE COMPRISING THE ORGANIC ELECTRONIC DEVICE Novaled GmbH (DE) 2025-11-05 EP disclosed
EP-4646075-A1 ORGANIC PHOTODETECTOR, ORGANIC ELECTRONIC DEVICE COMPRISING THE ORGANIC PHOTOTECTOR AS WELL AS A DISPLAY DEVICE COMPRISING THE ORGANIC ELECTRONIC DEVICE Novaled GmbH (DE) 2025-11-05 EP disclosed
EP-4600240-A1 ORGANIC ELECTRONIC DEVICE COMPRISING A METAL COMPLEX OF FORMULA (I) AS WELL AS A DISPLAY DEVICE COMPRISING THE ORGANIC ELECTRONIC DEVICE Novaled GmbH (DE) 2025-08-13 EP disclosed
EP-4601446-A1 ORGANIC PHOTODETECTOR COMPRISING A METAL COMPLEX OF FORMULA (I), AN ORGANIC ELECTRONIC DEVICE COMPRISING THE ORGANIC PHOTOTECTOR AS WELL AS A DISPLAY DEVICE COMPRISING THE ORGANIC ELECTRONIC DEVICE Novaled GmbH (DE) 2025-08-13 EP disclosed
EP-3171418-B1 ORGANIC SEMICONDUCTIVE LAYER COMPRISING PHOSPHINE OXIDE COMPOUNDS NOVALED GMBH (DE) 2024-12-11 EP disclosed
US-20240298524-A1 N-Doped Semiconducting Material Comprising Phosphine Oxide Matrix and Metal Dopant NOVALED GMBH (DE) 2024-09-05 US disclosed
US-20240147841-A1 Organic Semiconductive Layer Comprising Phosphine Oxide Compounds NOVALED GMBH (DE) 2024-05-02 US disclosed
EP-3109916-A1 ORGANIC LIGHT EMITTING DEVICE COMPRISING POLAR MATRIX, METAL DOPANT AND SILVER CATHODE Novaled GmbH (DE) 2016-12-28 EP disclosed
US-20160336516-A1 Semiconducting Material Comprising a Phosphepine Matrix Compound NOVALED GMBH (DE) 2016-11-17 US disclosed
US-20160336516-A1 Semiconducting Material Comprising a Phosphepine Matrix Compound NOVALED GMBH (DE) 2016-11-17 US disclosed
US-20160322568-A1 N-Doped Semiconducting Material Comprising Phosphine Oxide Matrix and Metal Dopant NOVALED GMBH (DE) 2016-11-03 US disclosed
US-20160322568-A1 N-Doped Semiconducting Material Comprising Phosphine Oxide Matrix and Metal Dopant NOVALED GMBH (DE) 2016-11-03 US disclosed
US-20160322568-A1 N-Doped Semiconducting Material Comprising Phosphine Oxide Matrix and Metal Dopant NOVALED GMBH (DE) 2016-11-03 US disclosed
EP-3087621-A1 N-DOPED SEMICONDUCTING MATERIAL COMPRISING PHOSPHINE OXIDE MATRIX AND METAL DOPANT Novaled GmbH (DE) 2016-11-02 EP disclosed
US-20150287930-A1 Phosphorescent OLED and Hole Transporting Materials for Phosphorescent OLEDS NOVALED GMBH (DE) 2015-10-08 US disclosed
US-20150287930-A1 Phosphorescent OLED and Hole Transporting Materials for Phosphorescent OLEDS NOVALED GMBH (DE) 2015-10-08 US disclosed
US-20150287930-A1 Phosphorescent OLED and Hole Transporting Materials for Phosphorescent OLEDS NOVALED GMBH (DE) 2015-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240147841-A1 Organic Semiconductive Layer Comprising Phosphine Oxide Compounds ALK, OR10J3, CCNT1 TNKS2 2889/4885PSMB5 4031/4885HSD17B1 2662/4885
US-20160322568-A1 N-Doped Semiconducting Material Comprising Phosphine Oxide Matrix and Metal Dopant NNMT, PNN, PNMT TNKS2 2213/4885PSMB5 4704/4885HSD17B1 4701/4885
US-20240298524-A1 N-Doped Semiconducting Material Comprising Phosphine Oxide Matrix and Metal Dopant NNMT, PNN, PNMT TNKS2 2213/4885PSMB5 4704/4885HSD17B1 4701/4885
US-20160336516-A1 Semiconducting Material Comprising a Phosphepine Matrix Compound NES, BMI1, PIN1 TNKS2 2060/4885PSMB5 3882/4885HSD17B1 4049/4885
US-20150287930-A1 Phosphorescent OLED and Hole Transporting Materials for Phosphorescent OLEDS SLC29A1, SLC43A3, SLC29A2 TNKS2 2740/4885PSMB5 3545/4885HSD17B1 2825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.