SCHEMBL17138384

SCHEMBL17138384

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nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
KDM4E B2RXH2 3/20 0.41
HTT P42858 2/20 0.38
TP53 P04637 2/20 0.38
EGLN1 Q9GZT9 1/20 0.38
EGLN3 Q9H6Z9 1/20 0.38
LMNA P02545 1/20 0.35
KMT2A Q03164 1/20 0.33
POLB P06746 2/20 0.32
MAPT P10636 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
ALDH1A1 P00352 1/20 0.32
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8846164 0.96 TSHR (0.39) TSHRKDM4EHTTTP53EGLN1
SCHEMBL269971 0.92 TSHR (0.41) TSHRKDM4EHTTTP53EGLN1
SCHEMBL8013 0.83 TSHR (0.36) TSHRKDM4EHTTTP53EGLN1
SCHEMBL28442624 0.83 TSHR (0.36) TSHRKDM4EHTTTP53EGLN1
SCHEMBL27902931 0.81 LDHA (0.44) TSHRKDM4EHTTTP53EGLN1
SCHEMBL11511298 0.81 LMNA (0.35) TSHRKDM4EHTTTP53EGLN1
SCHEMBL7779226 0.81 LDHA (0.44) TSHRKDM4EHTTTP53EGLN1
SCHEMBL11020165 0.81 HTT (0.42) TSHRKDM4EHTTTP53EGLN1
SCHEMBL11020169 0.81 HTT (0.42) TSHRKDM4EHTTTP53EGLN1
SCHEMBL29287334 0.78 HTT (0.41) TSHRKDM4EHTTKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3229075-B1 PHOTORESIST COMPOSITION, METHOD FOR MANUFACTURING SAME, AND METHOD FOR FORMING RESIST PATTERN JSR CORP (JP) 2021-01-06 EP disclosed
US-10725376-B2 Pattern-forming method JSR CORPORATION (JP) 2020-07-28 US disclosed
US-20190094689-A1 RADIATION-SENSITIVE COMPOSITION AND PATTERN-FORMING METHOD JSR CORPORATION (JP) 2019-03-28 US disclosed
US-10209619-B2 Composition and method of forming pattern using composition JSR CORPORATION (JP) 2019-02-19 US disclosed
US-10090163-B2 Inorganic film-forming composition for multilayer resist processes, and pattern-forming method JSR CORPORATION (JP) 2018-10-02 US disclosed
US-20170362412-A1 COMPOSITION FOR FILM FORMATION, AND PATTERN-FORMING METHOD JSR CORPORATION (JP) 2017-12-21 US disclosed
EP-3229075-A1 PHOTORESIST COMPOSITION, METHOD FOR MANUFACTURING SAME, AND METHOD FOR FORMING RESIST PATTERN JSR Corporation (JP) 2017-10-11 EP disclosed
US-20170269476-A1 PHOTORESIST COMPOSITION, PRODUCTION METHOD OF PHOTORESIST COMPOSITION, AND RESIST PATTERN-FORMING METHOD JSR CORPORATION (JP) 2017-09-21 US disclosed
US-20170184961-A1 PATTERN-FORMING METHOD JSR CORPORATION (JP) 2017-06-29 US disclosed
US-20160349616-A1 SEMICONDUCTOR DEVICE PRODUCTION COMPOSITION AND PATTERN FORMATION METHOD JSR CORPORATION (JP) 2016-12-01 US disclosed
US-20150364332-A1 INORGANIC FILM-FORMING COMPOSITION FOR MULTILAYER RESIST PROCESSES, AND PATTERN-FORMING METHOD JSR CORPORATION (JP) 2015-12-17 US disclosed
US-20150284539-A1 COMPOSITION FOR FILM FORMATION, AND PATTERN-FORMING METHOD JSR CORPORATION (JP) 2015-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10090163-B2 Inorganic film-forming composition for multilayer resist processes, and pattern-forming method HCAR1, HSD17B7, BMPR1A TSHR 1437/4885KDM4E 1112/4885HTT 1631/4885
US-20150364332-A1 INORGANIC FILM-FORMING COMPOSITION FOR MULTILAYER RESIST PROCESSES, AND PATTERN-FORMING METHOD HCAR1, HSD17B7, BMPR1A TSHR 1437/4885KDM4E 1112/4885HTT 1631/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.