SCHEMBL269971

SCHEMBL269971

O=C(O)C=C(C(=O)O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
KDM4E B2RXH2 3/20 0.41
HTT P42858 2/20 0.38
TP53 P04637 2/20 0.38
EGLN1 Q9GZT9 1/20 0.38
EGLN3 Q9H6Z9 1/20 0.38
LMNA P02545 1/20 0.35
KMT2A Q03164 1/20 0.33
POLB P06746 2/20 0.32
MAPT P10636 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
ALDH1A1 P00352 1/20 0.32
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17138384 0.92 TSHR (0.41) TSHRKDM4EHTTTP53EGLN1
SCHEMBL8846164 0.89 TSHR (0.39) TSHRKDM4EHTTTP53EGLN1
SCHEMBL8013 0.83 TSHR (0.36) TSHRKDM4EHTTTP53EGLN1
SCHEMBL28442624 0.83 TSHR (0.36) TSHRKDM4EHTTTP53EGLN1
SCHEMBL11020165 0.81 HTT (0.42) TSHRKDM4EHTTTP53EGLN1
SCHEMBL11511298 0.81 LMNA (0.35) TSHRKDM4EHTTTP53EGLN1
SCHEMBL27902931 0.81 LDHA (0.44) TSHRKDM4EHTTTP53EGLN1
SCHEMBL7779226 0.81 LDHA (0.44) TSHRKDM4EHTTTP53EGLN1
SCHEMBL11020169 0.81 HTT (0.42) TSHRKDM4EHTTTP53EGLN1
SCHEMBL28478051 0.78 HTT (0.41) TSHRKDM4EHTTKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1688 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042269-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US claimed
US-20260042268-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US claimed
US-20250387989-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2025-12-25 US claimed
EP-4657145-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
EP-4657144-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
EP-4571370-A2 METHOD FOR PRODUCING SILICON HYDROGEL CONTACT LENSES WITH CROSSLINKED HYDROPHILIC COATINGS THEREON Alcon Inc. (CH) 2025-06-18 EP claimed
EP-4553545-A2 METHOD FOR PRODUCING SILICON HYDROGEL CONTACT LENSES WITH CROSSLINKED HYDROPHILIC COATINGS THEREON Alcon Inc. (CH) 2025-05-14 EP claimed
EP-2598938-B1 Method for producing silicon hydrogel contact lenses with crosslinked hydrophilic coatings thereon ALCON INC (CH) 2025-01-29 EP claimed
CN-118084055-A Sodium chromite material and preparation method and application thereof 广东邦普循环科技有限公司 2024-05-28 CN claimed
EP-2880144-B1 BIODEGRADABLE STABILITY BINDING AGENT FOR A SOLID DETERGENT ECOLAB USA INC (US) 2024-05-01 EP claimed
US-6239230-B1 APPLYING A HYDROXYALKYLAMIDE, AND HEATING THE SURFACE-TREATED SUPERABSORBENT POLYMER PARTICLES TO CROSSLINK MOLECULAR CHAINS EXISTING AT LEAST IN THE VICINITY OF THE SURFACES OF THE SUPERABSORBENT POLYMER PARTICLES BASK AKTIENGESELLSCHAFT (DE) 2001-05-29 US claimed
US-6235102-B1 POLYMERS FOR COATING METAL SUBSTRATES THE VALSPAR CORPORATION 2001-05-22 US claimed
US-6229062-B1 WITH CYCLODEXTRAN, TRICLOSAN, AMPHOTERIC SURFACTANT, OR WATER INSOLUBLE PHOSPHATE AS ODOR CONTROLLER HOMOGENOUSLY DISTRIBUTED IN POLYMER; USED IN BANDAGES, DIAPERS, SANITARY NAPKINS, AND OTHER DIPOSABLE PAPER PRODUCTS BASF AKTIENGESELLSCHAFT CORPORATION (DE) 2001-05-08 US claimed
WO-2001030496-A1 MULTICOMPONENT ION EXCHANGE RESINS BASF AKTIENGESELLSCHAFT (DE) 2001-05-03 WO claimed
WO-2001030495-A1 ION EXCHANGE RESINS AND METHODS OF MAKING THE SAME BASF AKTIENGESELLSCHAFT (DE) 2001-05-03 WO claimed
WO-2000066187-A1 SUPERABSORBENT POLYMER CONTAINING ODOR CONTROLLING COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2000-11-09 WO claimed
WO-2000066670-A1 CROSSLINKABLE COATING COMPOSITION THE VALSPAR CORPORATION (US) 2000-11-09 WO claimed
WO-2000055245-A1 COLOR-STABLE SUPERABSORBENT POLYMER COMPOSITION BASF AKTIENGESELLSCHAFT (DE) 2000-09-21 WO claimed
EP-0727448-B1 Water soluble polymers containing allyloxybenzene sulfonic acid monomer and methallyl sulfonic acid monomer NAT STARCH CHEM INVEST (US) 1998-06-17 EP claimed
US-4330459-A Method of manufacturing foundry sand molds KURARAY COMPANY, LTD. (JP) 1982-05-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042269-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES CRYZ, STRA6, PHOSPHO1 TSHR 2055/4885KDM4E 1450/4885HTT 3461/4885
US-20260042268-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES STRA6, CRYZ, SMCHD1 TSHR 1985/4885KDM4E 1841/4885HTT 1546/4885
US-20250387989-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES PHOSPHO1, MYOC, ASS1 TSHR 1508/4885KDM4E 3432/4885HTT 2022/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.