Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1163485 | 0.88 | HTR2A (0.50) | HTR2AHTR1DTRPM8TAAR1HTR6 | |
| SCHEMBL3804876 | 0.86 | HTR2A (0.48) | HTR2AHTR1DTRPM8TAAR1HTR6 | |
| SCHEMBL1163144 | 0.86 | HTR2A (0.48) | HTR2AHTR1DTRPM8TAAR1HTR6 | |
| SCHEMBL3182087 | 0.85 | HTR2A (0.47) | HTR2AHTR1DTRPM8TAAR1HTR6 | |
| SCHEMBL3183284 | 0.84 | HTR2A (0.46) | HTR2AHTR1DTRPM8TAAR1HTR6 | |
| SCHEMBL3806838 | 0.84 | HTR2A (0.47) | HTR2AHTR1DTRPM8TAAR1HTR6 | |
| SCHEMBL16509893 | 0.84 | HTR2A (0.47) | HTR2AHTR1DTRPM8TAAR1HTR6 | |
| SCHEMBL3176490 | 0.83 | HTR6 (0.46) | HTR2AHTR1DTRPM8HTR6EGFR | |
| SCHEMBL3167331 | 0.83 | HTR6 (0.46) | HTR2AHTR1DTRPM8HTR6EGFR | |
| SCHEMBL17150095 | 0.83 | HTR1A (0.38) | HTR2AHTR1DTAAR1HTR6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150284365-A1 | COMPOUNDS AND METHODS OF USE THEREOF | GALENEA CORPORATION (US) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284365-A1 | COMPOUNDS AND METHODS OF USE THEREOF | AANAT, HNMT, INMT | HTR2A 34/4885HTR1D 154/4885TRPM8 2766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.