Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22617516 | 0.73 | HCAR2 (0.46) | KDM4ECYP11B2CYP11B1HSD17B1HSD17B2 | |
| SCHEMBL17488376 | 0.71 | PIM1 (0.40) | CYP11B2CYP11B1PIK3CGPIM1POLQ | |
| SCHEMBL10182122 | 0.69 | KDM4E (0.36) | KDM4EHSD17B1HSD17B2PIK3CGPTGDR2 | |
| SCHEMBL290909 | 0.68 | PIK3CG (0.35) | CYP11B2CYP11B1HSD17B1HSD17B2PIK3CG | |
| SCHEMBL290908 | 0.68 | CYP11B2 (0.38) | CYP11B2CYP11B1PIM1CYP3A4PTGDR2 | |
| SCHEMBL17082452 | 0.67 | CYP11B1 (0.39) | CYP11B2CYP11B1PIK3CGPIM1CYP17A1 | |
| SCHEMBL26847502 | 0.67 | CYP11B1 (0.39) | CYP11B2CYP11B1PIK3CGPIM1CYP17A1 | |
| SCHEMBL22617515 | 0.67 | TRPM8 (0.43) | KDM4ESMN1; SMN2POLQ | |
| Ammonia Solution, Strong SCHEMBL28242958 | 0.66 | HCAR2 (0.50) | CYP11B2CYP11B1HCAR2PIM1CYP17A1 | |
| SCHEMBL17589770 | 0.65 | CYP11B1 (0.38) | CYP11B2CYP11B1PIK3CGPIM1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611299-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012030681-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-03-08 | — | — | WO | disclosed |