Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488376 | 0.78 | PIM1 (0.40) | PIK3CGPIM1POLQCYP11B2CYP11B1 | |
| Hydrochloric Acid SCHEMBL28426809 | 0.77 | PTPN11 (0.46) | APPNPC1RAB9ASMN1; SMN2PTPN11 | |
| SCHEMBL174398 | 0.75 | KDM4E (0.53) | PIK3CGPIM1CYP2C9CYP2C19POLQ | |
| SCHEMBL290706 | 0.75 | SYK (0.39) | PIK3CGPOLQDYRK1AABL1CYP17A1 | |
| SCHEMBL18569045 | 0.74 | PIM1 (0.35) | PIK3CGPIM1POLQAPPCYP11B2 | |
| SCHEMBL290713 | 0.73 | APP (0.38) | PIK3CGPIM1CYP3A4CYP2C19APP | |
| SCHEMBL291163 | 0.72 | CYP2A6 (0.61) | CYP2E1CYP3A4CYP2D6CYP2A6CYP2C9 | |
| Hydrochloric Acid SCHEMBL17629274 | 0.72 | APP (0.37) | PIK3CGPIM1CYP3A4CYP2C19APP | |
| SCHEMBL290908 | 0.71 | CYP11B2 (0.38) | PIM1CYP2E1CYP3A4CYP2D6CYP2A6 | |
| SCHEMBL18569239 | 0.71 | APP (0.36) | PIK3CGPIM1CYP3A4CYP2C19APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614826-B1 | Process for preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2017-03-01 | — | — | EP | disclosed |
| US-9357780-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2016-06-07 | — | — | US | disclosed |
| EP-2614825-B1 | Process for the preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2016-03-16 | — | — | EP | disclosed |
| EP-2427191-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-03-16 | — | — | EP | disclosed |
| EP-2604267-B1 | Process for the preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2016-02-03 | — | — | EP | disclosed |
| EP-2604268-B1 | Process for the preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2015-09-16 | — | — | EP | disclosed |
| US-9006446-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-04-14 | — | — | US | disclosed |
| US-20150045218-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2015-02-12 | — | — | US | disclosed |
| US-20140348947-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-11-27 | — | — | US | disclosed |
| US-8853246-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2014-10-07 | — | — | US | disclosed |
| EP-2614825-A1 | Process for the preparation of thiazole derivatives | Dow AgroSciences LLC (US) | 2013-07-17 | — | — | EP | disclosed |
| EP-2614826-A1 | Process for preparation of thiazole derivatives | Dow AgroSciences LLC (US) | 2013-07-17 | — | — | EP | disclosed |
| EP-2604268-A1 | Process for the preparation of thiazole derivatives | Dow AgroSciences LLC (US) | 2013-06-19 | — | — | EP | disclosed |
| EP-2604267-A1 | Process for the preparation of thiazole derivatives | Dow AgroSciences LLC (US) | 2013-06-19 | — | — | EP | disclosed |
| US-20130089622-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130072382-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-8350044-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2013-01-08 | — | — | US | disclosed |
| EP-2427191-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2012-03-14 | — | — | EP | disclosed |
| US-20100292253-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2010-11-18 | — | — | US | disclosed |
| WO-2010129497-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292253-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | PIK3CG 795/4885PIM1 3309/4885CYP2E1 670/4885 |
| US-20130089622-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | PIK3CG 795/4885PIM1 3309/4885CYP2E1 670/4885 |
| US-20140348947-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | PIK3CG 795/4885PIM1 3309/4885CYP2E1 670/4885 |
| US-20150045218-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | PIK3CG 795/4885PIM1 3309/4885CYP2E1 670/4885 |
| US-20130072382-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | PIK3CG 795/4885PIM1 3309/4885CYP2E1 670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.