Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 5/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | HSD17B13 | Q7Z5P4 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18667384 | 0.78 | LOXL2 (0.42) | CYP11B2CYP11B1IRAK4HDAC6LOX | |
| Hydrochloric Acid SCHEMBL18641440 | 0.77 | MAOB (0.42) | CYP11B2CYP11B1IRAK4HDAC6LOX | |
| SCHEMBL17488376 | 0.75 | PIM1 (0.40) | CYP11B2CYP11B1PIM1 | |
| Hydrochloric Acid SCHEMBL18641515 | 0.72 | LOXL2 (0.38) | CYP11B2CYP11B1IRAK4CYP2A6CYP2E1 | |
| SCHEMBL18569045 | 0.71 | PIM1 (0.35) | CYP11B2CYP11B1IRAK4PIM1 | |
| SCHEMBL290909 | 0.71 | PIK3CG (0.35) | CYP11B2CYP11B1CYP2A6CYP2E1CYP3A4 | |
| SCHEMBL3492794 | 0.70 | CYP11B1 (0.53) | CYP11B2CYP11B1IRAK4CYP2A6CYP2E1 | |
| Hydrochloric Acid SCHEMBL15757346 | 0.69 | CYP11B1 (0.51) | CYP11B2CYP11B1IRAK4CYP2A6CYP2E1 | |
| SCHEMBL252833 | 0.69 | CYP2A6 (0.53) | CYP11B2CYP11B1CYP2A6PIM1LOXL2 | |
| SCHEMBL18641439 | 0.68 | EPHX2 (0.47) | CYP11B2CYP11B1IRAK4LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614826-B1 | Process for preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2017-03-01 | — | — | EP | disclosed |
| US-9357780-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2016-06-07 | — | — | US | disclosed |
| EP-2614825-B1 | Process for the preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2016-03-16 | — | — | EP | disclosed |
| EP-2427191-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-03-16 | — | — | EP | disclosed |
| EP-2604267-B1 | Process for the preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2016-02-03 | — | — | EP | disclosed |
| EP-2604268-B1 | Process for the preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2015-09-16 | — | — | EP | disclosed |
| US-9006446-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-04-14 | — | — | US | disclosed |
| US-20150045218-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2015-02-12 | — | — | US | disclosed |
| US-20140348947-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-11-27 | — | — | US | disclosed |
| US-8853246-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2014-10-07 | — | — | US | disclosed |
| EP-2614825-A1 | Process for the preparation of thiazole derivatives | Dow AgroSciences LLC (US) | 2013-07-17 | — | — | EP | disclosed |
| EP-2614826-A1 | Process for preparation of thiazole derivatives | Dow AgroSciences LLC (US) | 2013-07-17 | — | — | EP | disclosed |
| EP-2604268-A1 | Process for the preparation of thiazole derivatives | Dow AgroSciences LLC (US) | 2013-06-19 | — | — | EP | disclosed |
| EP-2604267-A1 | Process for the preparation of thiazole derivatives | Dow AgroSciences LLC (US) | 2013-06-19 | — | — | EP | disclosed |
| US-20130089622-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130072382-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-8350044-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2013-01-08 | — | — | US | disclosed |
| EP-2427191-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2012-03-14 | — | — | EP | disclosed |
| US-20100292253-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2010-11-18 | — | — | US | disclosed |
| WO-2010129497-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292253-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | CYP11B2 699/4885CYP11B1 821/4885IRAK4 4770/4885 |
| US-20130089622-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | CYP11B2 699/4885CYP11B1 821/4885IRAK4 4770/4885 |
| US-20140348947-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | CYP11B2 699/4885CYP11B1 821/4885IRAK4 4770/4885 |
| US-20150045218-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | CYP11B2 699/4885CYP11B1 821/4885IRAK4 4770/4885 |
| US-20130072382-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | CYP11B2 699/4885CYP11B1 821/4885IRAK4 4770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.