SCHEMBL17152102

SCHEMBL17152102

CC1(C)c2ccccc2-c2cc(-c3ccc4ccccc4c3-c3nc(-c4ccccc4-c4ccccc4)nc(-c4ccccc4-c4ccccc4)n3)ccc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 2/20 0.34
RARG P13631 2/20 0.34
RXRA P19793 2/20 0.34
DNMT1 P26358 1/20 0.31
PDE4A P27815 2/20 0.31
PDE4B Q07343 2/20 0.31
PDE4C Q08493 2/20 0.31
PDE4D Q08499 2/20 0.31
PDE3B Q13370 2/20 0.31
PDE7A Q13946 2/20 0.31
PDE3A Q14432 2/20 0.31
PDE7B Q9NP56 2/20 0.31
GPR84 Q9NQS5 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
NFKB1 P19838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17152003 0.94 RARB (0.34) RARBRARGRXRADNMT1PDE4A
SCHEMBL17151837 0.92 MAPT (0.34) RARBRARGRXRADNMT1GPR84
SCHEMBL18386104 0.92 PDE4A (0.33) RARBRARGRXRADNMT1PDE4A
SCHEMBL17151866 0.91 S1PR1 (0.35) DNMT1KDM4EALDH1A1TP53MAPT
SCHEMBL17152039 0.89 PDK2 (0.33) RARBRARGPDE7APDE7BKDM4E
SCHEMBL29311183 0.89 RARB (0.33) RARBRARGRXRAKDM4EALDH1A1
SCHEMBL18386082 0.89 GPR84 (0.32) DNMT1GPR84ALDH1A1HSD17B10
SCHEMBL17152099 0.88 RARB (0.38) RARBRARGRXRAKDM4EALDH1A1
SCHEMBL25679960 0.88 ENPP3 (0.33) RARBRARGRXRADNMT1GPR84
SCHEMBL17152091 0.87 DNMT1 (0.31) DNMT1ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024114-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2023-01-26 US disclosed
US-20220376178-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2022-11-24 US disclosed
US-10381572-B2 Heterocyclic compound and organic light-emitting element comprising same LG CHEM, LTD. (KR) 2019-08-13 US disclosed
US-20170018718-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2017-01-19 US disclosed
US-20170018718-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2017-01-19 US disclosed
WO-2015152651-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME 주식회사 엘지화학 2015-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10381572-B2 Heterocyclic compound and organic light-emitting element comprising same CRY1, CRY2, PER2 RARB 350/4885RARG 190/4885RXRA 368/4885
US-20170018718-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, PER2 RARB 350/4885RARG 190/4885RXRA 368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.