Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30509874 | 0.83 | NNMT (0.45) | TDP1POLBGPBAR1MAP3K5SIRT6 | |
| SCHEMBL3518155 | 0.83 | KDM4E (0.42) | TDP1GPBAR1MAP3K5LMNACYP17A1 | |
| SCHEMBL31582882 | 0.83 | NNMT (0.45) | TDP1POLBGPBAR1MAP3K5SIRT6 | |
| SCHEMBL27185528 | 0.81 | KMT2A (0.42) | HCAR2GPBAR1LMNAGABRPGABRD | |
| SCHEMBL30421542 | 0.81 | KMT2A (0.42) | HCAR2GPBAR1LMNAGABRPGABRD | |
| SCHEMBL17157430 | 0.78 | GPBAR1 (0.43) | GPBAR1MAP3K5CYP17A1KDM4EALDH1A1 | |
| SCHEMBL18033428 | 0.76 | PRSS1 (0.33) | GPBAR1MAP3K5CYP17A1SIRT6 | |
| SCHEMBL24729209 | 0.74 | L3MBTL1 (0.52) | TDP1POLBLMNAKMT2AMEN1 | |
| SCHEMBL27906709 | 0.74 | CASP3 (0.44) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL29364820 | 0.74 | HPGD (0.47) | TDP1HCAR2GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642450-A2 | EP2 ANTAGONIST COMPOUNDS | Reservoir Neuroscience, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| EP-3562306-B1 | METALLOENZYME INHIBITOR COMPOUNDS | JI XING PHARMACEUTICALS HONG KONG LTD (HK) | 2025-02-26 | — | — | EP | disclosed |
| US-20240246952-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-07-25 | — | — | US | disclosed |
| WO-2024145259-A2 | EP2 ANTAGONIST COMPOUNDS | RESERVOIR NEUROSCIENCE, INC. (US) | 2024-07-04 | — | — | WO | disclosed |
| US-20240109899-A1 | BENZOFURAN COMPOUNDS AS STING AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-04-04 | — | — | US | disclosed |
| CN-117751114-A | Small molecule modulators of glucocerebrosidase activity and uses thereof | 凡况生化公司 | 2024-03-22 | — | — | CN | disclosed |
| EP-4329880-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-03-06 | — | — | EP | disclosed |
| US-11919883-B2 | Metalloenzyme inhibitor compounds | JI XING PHARMACEUTICALS HONG KONG LIMITED (HK) | 2024-03-05 | — | — | US | disclosed |
| CN-109956929-B | Heterocyclic derivative, preparation method, pharmaceutical composition and application thereof | 上海迪诺医药科技有限公司 | 2023-09-19 | — | — | CN | disclosed |
| EP-3600312-B1 | PIPERIDINYL- AND PIPERAZINYL-SUBSTITUTED HETEROAROMATIC CARBOXAMIDES AS MODULATORS OF GPR6 | TAKEDA PHARMACEUTICALS CO (JP) | 2023-05-17 | — | — | EP | disclosed |
| US-9944664-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2018-04-17 | — | — | US | disclosed |
| US-9944664-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2018-04-17 | — | — | US | disclosed |
| US-9944664-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2018-04-17 | — | — | US | disclosed |
| EP-3131399-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | Dow AgroSciences LLC (US) | 2017-02-22 | — | — | EP | disclosed |
| CN-106231901-A | Metal enzyme inhibitor compound as antifungal | 美国陶氏益农公司 | 2016-12-14 | — | — | CN | disclosed |
| WO-2015160665-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2015-10-22 | — | — | WO | disclosed |
| WO-2015160665-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2015-10-22 | — | — | WO | disclosed |
| US-20150291632-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-10-15 | — | — | US | disclosed |
| US-20150291632-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-10-15 | — | — | US | disclosed |
| US-20150291632-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291632-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | GPX1, POR, MGAM | TDP1 1526/4885POLB 3948/4885HCAR2 4224/4885 |
| US-20240109899-A1 | BENZOFURAN COMPOUNDS AS STING AGONISTS | STING1, MAVS, IRF3 | TDP1 262/4885POLB 1220/4885HCAR2 1189/4885 |
| US-20240246952-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | GBA1, GAA, GBA2 | TDP1 483/4885POLB 1535/4885HCAR2 2641/4885 |
| US-11919883-B2 | Metalloenzyme inhibitor compounds | SOD1, RNASE1, FECH | TDP1 1270/4885POLB 1401/4885HCAR2 4401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.