Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.48 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.48 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12696346 | 1.00 | TBXAS1 (0.53) | TBXAS1PPARGPPARAPTGS1PTGS2 | |
| SCHEMBL10081972 | 1.00 | TBXAS1 (0.53) | TBXAS1PPARGPPARAPTGS1PTGS2 | |
| SCHEMBL11237591 | 0.91 | TBXAS1 (0.59) | TBXAS1PTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL11615201 | 0.85 | ACACB (0.47) | PPARGPPARAPTGS1PTGS2LMNA | |
| SCHEMBL19553694 | 0.85 | PTGS1 (0.66) | TBXAS1PTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL22184250 | 0.85 | MME (0.46) | TBXAS1PPARGPPARAPTGS1PTGS2 | |
| SCHEMBL15147780 | 0.85 | MME (0.46) | TBXAS1PPARGPPARAPTGS1PTGS2 | |
| SCHEMBL14499001 | 0.83 | ACACB (0.50) | PPARGPPARAPTGS1PTGS2LMNA | |
| SCHEMBL284670 | 0.83 | SLC7A5 (0.60) | TBXAS1PTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL11996333 | 0.83 | TBXAS1 (0.53) | TBXAS1PPARGPPARAPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103724244-B | Thiourea is as the application of solid nitration reagent | XI'AN JIAOTONG UNIVERSITY (CN) | 2015-08-26 | — | — | CN | claimed |
| CN-103724244-A | Application of thiourea nitrate as solid nitration reagent | UNIV XI AN JIAOTONG | 2014-04-16 | — | — | CN | claimed |
| CN-102146049-A | Synthetic method of thiourea nitrate and application of thiourea nitrate as solid nitration reagent | UNIV XIAN JIAOTONG | 2011-08-10 | — | — | CN | claimed |
| EP-1716159-B1 | BICYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2011-07-13 | — | — | EP | claimed |
| EP-1697386-B1 | ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES | GEN ELECTRIC (US) | 2007-10-10 | — | — | EP | claimed |
| EP-0428276-B1 | Acaricidal composition | TAKASAGO PERFUMERY CO LTD (JP) | 1998-09-16 | — | — | EP | claimed |
| US-20230147021-A1 | POLYSULFIDE STABILIZATION | UNIVERSITY PUBLIC CORPORATION OSAKA (JP) | 2023-05-11 | — | — | US | disclosed |
| WO-2022121844-A1 | DIHYDROPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 上海维申医药有限公司 | 2022-06-16 | — | — | WO | disclosed |
| CN-109456324-B | Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-04-22 | — | — | CN | disclosed |
| EP-2145042-B2 | TEXTILE SCENTING | HENKEL AG & CO KGAA (DE) | 2021-10-06 | — | — | EP | disclosed |
| US-11028070-B2 | Isoindoline or isoquinoline compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2021-06-08 | — | — | US | disclosed |
| US-20200262816-A1 | ISOINDOLINE OR ISOQUINOLINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2020-08-20 | — | — | US | disclosed |
| US-10689364-B2 | Isoindoline or isoquinoline compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2020-06-23 | — | — | US | disclosed |
| WO-2007070041-A1 | HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-06-21 | — | — | WO | disclosed |
| US-20070135595-A1 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS, INC. | 2007-06-14 | — | — | US | disclosed |
| US-7160874-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2007-01-09 | — | — | US | disclosed |
| EP-1337532-B1 | COMPOUND FOR CHELATING A METAL, RADIOPHARMACEUTICAL, MANUFACTURING PROCESS THEREFOR, AND DIAGNOSTIC KIT | SCHERING AG (DE) | 2005-05-11 | — | — | EP | disclosed |
| US-20040043920-A1 | Compound for chelating a metal, radiopharmaceutical, manufacturing process therefor, and diagnostic kit | SCHERING AG (DE) | 2004-03-04 | — | — | US | disclosed |
| EP-0292889-B1 | BENZALDEHYDE DERIVATIVES, THEIR PREPARATION AND USE | BASF Aktiengesellschaft (DE) | 1992-09-02 | — | — | EP | disclosed |
| EP-0292889-A2 | Benzaldehyde derivatives, their preparation and use | BASF Aktiengesellschaft (DE) | 1988-11-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043920-A1 | Compound for chelating a metal, radiopharmaceutical, manufacturing process therefor, and diagnostic kit | MC5R, SLC30A5, SENP5 | TBXAS1 4336/4885PPARG 4562/4885PPARA 4599/4885 |
| US-20070135595-A1 | Halogen substituted metallocene compounds for olefin polymerization | AP2M1, AP1M1, CPNE4 | TBXAS1 3732/4885PPARG 1347/4885PPARA 1595/4885 |
| US-20230147021-A1 | POLYSULFIDE STABILIZATION | YWHAZ, YWHAH, PTPN21 | TBXAS1 3223/4885PPARG 4696/4885PPARA 4796/4885 |
| US-20200262816-A1 | ISOINDOLINE OR ISOQUINOLINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BAX, RECQL, CASP7 | TBXAS1 729/4885PPARG 2316/4885PPARA 3184/4885 |
| US-10689364-B2 | Isoindoline or isoquinoline compounds, a process for their preparation and pharmaceutical compositions containing them | BAX, CASP7, CASP3 | TBXAS1 766/4885PPARG 2343/4885PPARA 3180/4885 |
| US-11028070-B2 | Isoindoline or isoquinoline compounds, a process for their preparation and pharmaceutical compositions containing them | BAX, RECQL, CASP7 | TBXAS1 729/4885PPARG 2316/4885PPARA 3184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.