SCHEMBL171663

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL171149	0.88	SIGMAR1 (0.50)	KDM4EALDH1A1SIGMAR1
	SCHEMBL13490577	0.81	LMNA (0.47)	ALDH1A1SIGMAR1
	SCHEMBL169524	0.81	ALDH1A1 (0.39)	ALDH1A1HPGDHTTSIGMAR1
	SCHEMBL169427	0.78	TRPV6 (0.37)	TRPV6MMP2MMP9KDM4EALDH1A1
	SCHEMBL13592661	0.77	TP53 (0.36)	HRH3KDM4EALDH1A1TDP1HPGD
	SCHEMBL13490589	0.77	MEN1 (0.42)	OPRK1SIGMAR1
	SCHEMBL13490578	0.77	ALDH1A1 (0.56)	KDM4EALDH1A1TDP1SIGMAR1
	SCHEMBL13592659	0.77	ACHE (0.36)	HRH3ALDH1A1SIGMAR1
	SCHEMBL171457	0.77	CCNT1 (0.37)	ALDH1A1SIGMAR1
	SCHEMBL13490576	0.76	SIGMAR1 (0.34)	KDM4EALDH1A1HTTSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.