Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17651664 | 1.00 | LMNA (0.48) | LMNATP53HSD11B1GRIK1GRIK2 | |
| SCHEMBL1716939 | 0.84 | PAM (0.53) | LMNASMN1; SMN2PPARACYP2C19 | |
| SCHEMBL1716940 | 0.84 | PAM (0.53) | LMNASMN1; SMN2PPARACYP2C19 | |
| SCHEMBL16213234 | 0.81 | PPARA (0.62) | GRIK1GRIK2PPARACYP2C19 | |
| SCHEMBL17651678 | 0.81 | PPARA (0.62) | GRIK1GRIK2PPARACYP2C19 | |
| SCHEMBL13153522 | 0.78 | NFE2L2 (0.48) | LMNATP53HSD11B1SMN1; SMN2PTGS1 | |
| SCHEMBL13181176 | 0.74 | LMNA (0.44) | LMNATP53HSD11B1SMN1; SMN2PTGS1 | |
| SCHEMBL10521642 | 0.73 | ACHE (0.43) | LMNATP53SMN1; SMN2PPARANFE2L2 | |
| SCHEMBL5311088 | 0.73 | PAM (0.68) | LMNATP53HSD11B1GRIK1GRIK2 | |
| SCHEMBL5311091 | 0.73 | PAM (0.68) | LMNATP53HSD11B1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10017441-B2 | Direct anti-markovnikov addition of acids to alkenes | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2018-07-10 | — | — | US | disclosed |
| US-20160096791-A1 | DIRECT ANTI-MARKOVNIKOV ADDITION OF ACIDS TO ALKENES | UNIV NORTH CAROLINA (US) | 2016-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160096791-A1 | DIRECT ANTI-MARKOVNIKOV ADDITION OF ACIDS TO ALKENES | HAO2, DUOX2, PDK2 | LMNA 3289/4885TP53 4661/4885HSD11B1 954/4885 |
| US-10017441-B2 | Direct anti-markovnikov addition of acids to alkenes | HAO2, DUOX2, PDK2 | LMNA 3289/4885TP53 4661/4885HSD11B1 954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.