SCHEMBL17178665

SCHEMBL17178665

c1ccc(-c2ccc(-n3c4ccccc4c4cc(-c5ccc6c(c5)c5ccccc5n6-c5ccc6c(c5)C(c5ccccc5)(c5ccccc5)c5ccccc5-6)ccc43)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PDK2 Q15119 2/20 0.35
TSPO P30536 1/20 0.34
HDAC4 P56524 1/20 0.34
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
OPRK1 P41145 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
EDNRB P24530 1/20 0.31
EDNRA P25101 1/20 0.31
DNM1 Q05193 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19980592 1.00 KDM4E (0.39) KDM4EATML3MBTL1PDK2TSPO
SCHEMBL24667556 1.00 KDM4E (0.39) KDM4EATML3MBTL1PDK2TSPO
SCHEMBL16596566 0.99 KDM4E (0.40) KDM4EATML3MBTL1PDK2TSPO
SCHEMBL24569001 0.99 KDM4E (0.36) KDM4EATML3MBTL1PDK2TSPO
SCHEMBL16596613 0.99 KDM4E (0.40) KDM4EATML3MBTL1PDK2TSPO
SCHEMBL22172948 0.98 KDM4E (0.37) KDM4EATML3MBTL1PDK2TSPO
SCHEMBL24667874 0.98 KDM4E (0.36) KDM4EATML3MBTL1PDK2TSPO
SCHEMBL24667875 0.98 KDM4E (0.36) KDM4EATML3MBTL1PDK2TSPO
SCHEMBL20232363 0.98 KDM4E (0.36) KDM4EATML3MBTL1PDK2TSPO
SCHEMBL19271571 0.96 KDM4E (0.40) KDM4EATML3MBTL1PDK2TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917907-B2 Organic electroluminescent device ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2024-02-27 US disclosed
US-11917907-B2 Organic electroluminescent device ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2024-02-27 US disclosed
US-20230049674-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-02-16 US disclosed
US-11535619-B2 Hexacyclic heteroaromatic compounds for electronic devices MERCK PATENT GMBH (DE) 2022-12-27 US disclosed
US-11527728-B2 Organic electroluminescent compounds and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2022-12-13 US disclosed
US-11447464-B2 Compounds with spirobifluorene-structures MERCK PATENT GMBH (DE) 2022-09-20 US disclosed
EP-3863077-B1 ORGANIC LIGHT EMITTING DEVICE LG CHEMICAL LTD (KR) 2022-05-04 EP disclosed
US-20220102633-A1 ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2022-03-31 US disclosed
EP-3863077-A1 ORGANIC LIGHT EMITTING DIODE LG Chem, Ltd. (KR) 2021-08-11 EP disclosed
EP-3512848-B1 COMPOUNDS WITH CARBAZOLE STRUCTURES MERCK PATENT GMBH (DE) 2020-11-18 EP disclosed
US-20170279056-A1 A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-09-28 US disclosed
US-20170213968-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-07-27 US disclosed
US-20170213968-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-07-27 US disclosed
US-20170207396-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-07-20 US disclosed
US-20170207396-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-07-20 US disclosed
US-20170170408-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-06-15 US disclosed
US-20170170408-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-06-15 US disclosed
US-20170117488-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-04-27 US disclosed
US-20170117488-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-04-27 US disclosed
WO-2015156587-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2015-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11447464-B2 Compounds with spirobifluorene-structures SLCO1B3, SLCO4C1, SLCO1B1 KDM4E 4250/4885ATM 2993/4885L3MBTL1 4742/4885
US-11527728-B2 Organic electroluminescent compounds and organic electroluminescent device comprising the same VDAC1, VDAC2, VAPA KDM4E 2458/4885ATM 2686/4885L3MBTL1 300/4885
US-20220102633-A1 ORGANIC ELECTROLUMINESCENT DEVICE SOD1, TRPC6, L1CAM KDM4E 2489/4885ATM 3395/4885L3MBTL1 62/4885
US-11535619-B2 Hexacyclic heteroaromatic compounds for electronic devices ETV6, CYP2J2, CYP2D6 KDM4E 2237/4885ATM 4482/4885L3MBTL1 3859/4885
US-20230049674-A1 ORGANIC LIGHT EMITTING DEVICE CRY2, ELOVL1, CRY1 KDM4E 2327/4885ATM 4301/4885L3MBTL1 213/4885
US-11917907-B2 Organic electroluminescent device SOD1, TRPC6, L1CAM KDM4E 2489/4885ATM 3395/4885L3MBTL1 62/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.