Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2493883 | 0.78 | KMT2A (0.51) | KMT2AALDH1A1GAANPSR1KDM4E | |
| SCHEMBL1522389 | 0.72 | ALDH1A1 (0.43) | KMT2AALDH1A1GAANPSR1KDM4E | |
| SCHEMBL1522388 | 0.72 | ALDH1A1 (0.43) | KMT2AALDH1A1GAANPSR1KDM4E | |
| SCHEMBL4150824 | 0.71 | MAPK8 (0.49) | KMT2AALDH1A1GAANPSR1KDM4E | |
| SCHEMBL17181704 | 0.71 | JAK3 (0.41) | ALDH1A1GAAKDM4EMAPTCYP1A2 | |
| SCHEMBL14208559 | 0.70 | MAPK10 (0.50) | KMT2AALDH1A1GAANPSR1KDM4E | |
| SCHEMBL17181711 | 0.70 | PTGS2 (0.40) | KMT2AALDH1A1GAANPSR1KDM4E | |
| SCHEMBL4141900 | 0.68 | PKM (0.76) | KMT2AALDH1A1GAAPKMMAPT | |
| SCHEMBL17181737 | 0.66 | HPGD (0.52) | KMT2AALDH1A1GAANPSR1KDM4E | |
| SCHEMBL22004182 | 0.63 | KMT2A (0.59) | KMT2AALDH1A1GAAMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935221-B1 | QUINOLONE DERIVATIVES | CADILA HEALTHCARE LTD (IN) | 2018-02-07 | — | — | EP | disclosed |
| US-9394300-B2 | Quinolone derivatives | CADILA HEALTHCARE LIMITED (IN) | 2016-07-19 | — | — | US | disclosed |
| US-20150299193-A1 | NOVEL QUINOLONE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2015-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150299193-A1 | NOVEL QUINOLONE DERIVATIVES | NQO2, UGT1A1, CYP11B2 | KMT2A 4449/4885ALDH1A1 2214/4885GAA 1331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.