Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.36 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.36 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11382111 | 0.78 | CTSD (0.47) | ALDH1A1GFERMAPTKDM4EMEN1 | |
| SCHEMBL17185444 | 0.77 | ALDH1A1 (0.44) | ALDH1A1GFERMAPTKDM4EMEN1 | |
| SCHEMBL1974542 | 0.74 | ALDH1A1 (0.48) | ALDH1A1GFERMAPTKDM4EMAP2K1 | |
| SCHEMBL2721634 | 0.73 | MAPT (0.53) | ALDH1A1GFERMAPTKDM4EMEN1 | |
| SCHEMBL15471934 | 0.71 | KDM4E (0.44) | ALDH1A1GFERMAPTKDM4EMAP2K1 | |
| SCHEMBL15471931 | 0.71 | ALDH1A1 (0.44) | ALDH1A1GFERMAPTKDM4EMAP2K1 | |
| SCHEMBL15471933 | 0.71 | ALDH1A1 (0.68) | ALDH1A1GFERMAPTKDM4EMEN1 | |
| SCHEMBL16192428 | 0.64 | ALDH1A1 (0.53) | ALDH1A1GFERMAPTKDM4EMEN1 | |
| SCHEMBL8272560 | 0.64 | SIRT2 (0.42) | ALDH1A1MAPTKDM4EMEN1MITF | |
| SCHEMBL27775502 | 0.64 | MGLL (0.48) | MEN1GAAKMT2ANPSR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015161014-A1 | HETEROCYCLIC CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2015-10-22 | — | — | WO | disclosed |