Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19426002 | 0.81 | CDK2 (0.36) | CDK2RNASEH1PTPN11 | |
| SCHEMBL17192085 | 0.78 | RNASEH1 (0.33) | RNASEH1 | |
| SCHEMBL17192059 | 0.75 | CDC42 (0.36) | RNASEH1 | |
| SCHEMBL17192067 | 0.71 | CDC42 (0.33) | — | |
| SCHEMBL19420582 | 0.70 | GABRA1 (0.34) | RNASEH1 | |
| SCHEMBL19426153 | 0.66 | PTPN22 (0.38) | CDK2RNASEH1 | |
| SCHEMBL15631181 | 0.65 | ALDH1A1 (0.36) | — | |
| SCHEMBL15632234 | 0.65 | CDK2 (0.39) | CDK2RNASEH1PTPN11 | |
| SCHEMBL19420607 | 0.63 | GABRA1 (0.34) | RNASEH1 | |
| SCHEMBL17192062 | 0.63 | GABRA1 (0.38) | CDK2RNASEH1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170281532-A1 | 2 SUBSTITUTED CEPHEM COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2017-10-05 | — | — | US | disclosed |
| US-20170281532-A1 | 2 SUBSTITUTED CEPHEM COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2017-10-05 | — | — | US | disclosed |
| US-20150299223-A1 | 2-SUBSTITUTED CEPHEM COMPOUNDS | GLAXO GROUP LTD (GB) | 2015-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170281532-A1 | 2 SUBSTITUTED CEPHEM COMPOUNDS | CEP170, CES2, CMBL | CDK2 528/4885RNASEH1 3539/4885PTPN11 3069/4885 |
| US-20150299223-A1 | 2-SUBSTITUTED CEPHEM COMPOUNDS | CEP170, ABL1, CEPT1 | CDK2 2785/4885RNASEH1 3773/4885PTPN11 2078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.