Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 6/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17794442 | 0.83 | CHRNB2 (0.40) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17190470 | 0.79 | MAPK1 (0.44) | MEN1KMT2ASMN1; SMN2MAPTRECQL | |
| SCHEMBL1679019 | 0.79 | TSHR (0.57) | TSHRALDH1A1POLBMEN1KMT2A | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL113765 | 0.79 | TSHR (0.57) | TSHRALDH1A1POLBMEN1KMT2A | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL3889276 | 0.79 | TSHR (0.57) | TSHRALDH1A1POLBMEN1KMT2A | |
| SCHEMBL31503973 | 0.78 | TSHR (0.50) | TSHRALDH1A1POLBMEN1KMT2A | |
| SCHEMBL7394679 | 0.78 | DPP4 (0.49) | TSHRALDH1A1POLBMEN1KMT2A | |
| SCHEMBL17791729 | 0.78 | CA2 (0.36) | ALDH1A1POLBKMT2ASMN1; SMN2TDP1 | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL11491904 | 0.77 | TSHR (0.55) | TSHRALDH1A1POLBMEN1KMT2A | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL28219889 | 0.77 | TSHR (0.55) | TSHRALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150344514-A1 | CHEMICALLY CLEAVABLE GROUP | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2015-12-03 | — | — | US | disclosed |
| US-20150297741-A1 | BIO-ORTHOGONAL DRUG ACTIVATION | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2015-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344514-A1 | CHEMICALLY CLEAVABLE GROUP | SQLE, CTRL, ENO1 | TSHR 2074/4885ALDH1A1 780/4885POLB 1630/4885 |
| US-20150297741-A1 | BIO-ORTHOGONAL DRUG ACTIVATION | KIT, JMJD7, TPSB2 | TSHR 1816/4885ALDH1A1 1711/4885POLB 2718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.