SCHEMBL17194302

SCHEMBL17194302

Cc1ccc(-c2ccc(S(=O)(=O)NCCCN3CCC(N4CCCCC4)CC3)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.70
▸ MBTD1 Q05BQ5 1/20 0.70
▸ ALDH1A1 P00352 2/20 0.52
▸ KDM4E B2RXH2 2/20 0.52
▸ HTR1A P08908 2/20 0.52
▸ MEN1 O00255 1/20 0.52
▸ KMT2A Q03164 1/20 0.52
▸ CCR1 P32246 1/20 0.50
▸ HRH3 Q9Y5N1 1/20 0.49
▸ POLB P06746 2/20 0.48
▸ GAA P10253 2/20 0.48
▸ TSHR P16473 1/20 0.48
▸ RECQL P46063 1/20 0.48
▸ NPSR1 Q6W5P4 1/20 0.48
▸ LMNA P02545 1/20 0.47
▸ MAPT P10636 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ HTR2A P28223 1/20 0.47
▸ SLC6A4 P31645 1/20 0.47
▸ HTR7 P34969 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18502078 0.97 L3MBTL1 (0.65) L3MBTL1MBTD1ALDH1A1KDM4EHTR1A
SCHEMBL18502083 0.91 MBTD1 (0.66) L3MBTL1MBTD1ALDH1A1KDM4EHTR1A
SCHEMBL18502069 0.90 MBTD1 (0.55) L3MBTL1MBTD1KDM4EHTR1AKMT2A
SCHEMBL18501758 0.89 L3MBTL1 (0.54) L3MBTL1MBTD1ALDH1A1KDM4EHTR1A
SCHEMBL18502084 0.89 KMT2A (0.60) L3MBTL1MBTD1ALDH1A1KDM4EKMT2A
SCHEMBL17194300 0.89 HTR7 (0.61) L3MBTL1MBTD1ALDH1A1HTR1AMEN1
SCHEMBL18506938 0.87 L3MBTL1 (0.52) L3MBTL1MBTD1KDM4EKMT2ACCR1
SCHEMBL18502080 0.87 HTR1A (0.52) L3MBTL1MBTD1KDM4EHTR1AGAA
SCHEMBL18507066 0.86 HTR7 (0.53) L3MBTL1MBTD1KDM4EHTR1AKMT2A
SCHEMBL17194235 0.85 SIGMAR1 (0.65) L3MBTL1MBTD1ALDH1A1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3131890-B1 COMPOUNDS FOR TREATING VIRAL INFECTIONS PASTEUR INSTITUT KOREA (KR) 2019-04-24 — — EP disclosed
US-9809602-B2 Compounds for treating viral infections INSTITUT PASTEUR KOREA (KR) 2017-11-07 — — US disclosed
US-9809602-B2 Compounds for treating viral infections INSTITUT PASTEUR KOREA (KR) 2017-11-07 — — US disclosed
US-20170044181-A1 COMPOUNDS FOR TREATING VIRAL INFECTIONS INSTITUT PASTEUR KOREA (KR) 2017-02-16 — — US disclosed
US-20170044181-A1 COMPOUNDS FOR TREATING VIRAL INFECTIONS INSTITUT PASTEUR KOREA (KR) 2017-02-16 — — US disclosed
WO-2015158908-A1 COMPOUNDS FOR TREATING VIRAL INFECTIONS INSTITUT PASTEUR KOREA (KR) 2015-10-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170044181-A1 COMPOUNDS FOR TREATING VIRAL INFECTIONS HAVCR2, MAVS, EIF2AK2 L3MBTL1 992/4885MBTD1 4074/4885ALDH1A1 676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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