Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18811696 | 0.80 | RIPK1 (0.40) | RIPK1DRD2KCNH2 | |
| SCHEMBL27094883 | 0.76 | CA2 (0.38) | — | |
| SCHEMBL17173639 | 0.74 | RIPK1 (0.39) | RIPK1 | |
| SCHEMBL17196423 | 0.72 | RIPK1 (0.37) | RIPK1HTR2AHTR2C | |
| SCHEMBL21089366 | 0.72 | RIPK1 (0.36) | RIPK1DRD2 | |
| SCHEMBL3433903 | 0.67 | MPO (0.43) | LRRK2 | |
| SCHEMBL29284948 | 0.67 | FPR2 (0.33) | — | |
| SCHEMBL29284986 | 0.67 | FPR2 (0.35) | — | |
| SCHEMBL3576265 | 0.63 | HCAR2 (0.42) | — | |
| SCHEMBL6079670 | 0.63 | BAZ2B (0.37) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015158427-A1 | HETEROARYL SUBSTITUTED HETEROCYCLYL SULFONES | Grünenthal GmbH (DE) | 2015-10-22 | — | — | WO | disclosed |