Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Proline SCHEMBL3105891 | 0.84 | KMT2A (0.38) | ALOX15BLMPMP22KMT2A | |
| SCHEMBL2043828 | 0.81 | NOS2 (0.37) | KMT2A | |
| Proline SCHEMBL140698 | 0.77 | TLR2 (0.34) | BLMKMT2A | |
| Serine SCHEMBL17199761 | 0.76 | ALOX15 (0.41) | ALOX15BLMPMP22KMT2A | |
| Alanine SCHEMBL5970554 | 0.76 | TLR2 (0.36) | KMT2A | |
| SCHEMBL1275426 | 0.76 | ALOX15 (0.38) | ALOX15BLMPMP22KMT2A | |
| Valine SCHEMBL4398679 | 0.76 | ALOX15 (0.31) | ALOX15BLMPMP22KMT2A | |
| Glutamine SCHEMBL19031701 | 0.75 | ALOX15 (0.43) | ALOX15BLMPMP22KMT2A | |
| Valine SCHEMBL18954803 | 0.74 | ALOX15 (0.37) | ALOX15BLMPMP22KMT2A | |
| Lysine SCHEMBL6151465 | 0.74 | GSR (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2937096-B1 | Peptides derived from RS1 which down-regulate glucose absorption after a glucose rich meal and increase insulin sensitivity | UNIV WUERZBURG J MAXIMILIANS (DE) | 2019-08-21 | — | — | EP | disclosed |
| US-10105414-B2 | Peptides derived from RS1 which down-regulate glucose absorption after a glucose rich meal and increase insulin sensitivity | JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) | 2018-10-23 | — | — | US | disclosed |
| US-20170042969-A1 | PEPTIDES DERIVED FROM RS1 WHICH DOWN-REGULATE GLUCOSE ABSORPTION AFTER A GLUCOSE RICH MEAL AND INCREASE INSULIN SENSITIVITY | JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) | 2017-02-16 | — | — | US | disclosed |
| WO-2015162214-A1 | PEPTIDES DERIVED FROM RS1 WHICH DOWN-REGULATE GLUCOSE ABSORPTION AFTER A GLUCOSE RICH MEAL AND INCREASE INSULIN SENSITIVITY | JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) | 2015-10-29 | — | — | WO | disclosed |
| EP-2937096-A1 | Peptides derived from RS1 which down-regulate glucose absorption after a glucose rich meal and increase insulin sensitivity | Julius-Maximilians-Universität Würzburg (DE) | 2015-10-28 | — | — | EP | disclosed |