Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | RXRB | P28702 | 2/20 | 0.35 |
| ▸ | RXRG | P48443 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | SLC26A3 | P40879 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3770067 | 0.86 | FFAR4 (0.32) | PTGS1PTGS2FFAR4 | |
| SCHEMBL3765142 | 0.84 | POLB (0.33) | POLBPTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL3763744 | 0.76 | AGBL2 (0.45) | AGBL2RXRARXRBRXRGTHRA | |
| SCHEMBL6995163 | 0.74 | AKR1C2 (0.50) | RXRARXRBRXRGCYP2C9AKR1C2 | |
| SCHEMBL3765069 | 0.73 | ALDH1A1 (0.34) | KDM4EPOLBMAPTCYP2C19TSHR | |
| SCHEMBL509440 | 0.69 | KDM4E (0.58) | AGBL2KDM4EPOLBMAPTCYP1A2 | |
| SCHEMBL2687552 | 0.69 | HTR1D (0.58) | AGBL2RXRARXRBRXRGKDM4E | |
| SCHEMBL9780872 | 0.68 | CYP3A4 (0.47) | AGBL2THRATHRBKDM4EPOLB | |
| Hydrochloric Acid SCHEMBL2529687 | 0.68 | KDM4E (0.56) | AGBL2KDM4EPOLBMAPTCYP1A2 | |
| Water SCHEMBL28215001 | 0.68 | KDM4E (0.56) | AGBL2KDM4EPOLBMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406216-B1 | HALOGENALKYLMETHYLENOXY-PHENYL-SUBSTITUTED KETOENOLS | BAYER IP GMBH (DE) | 2017-04-19 | — | — | EP | disclosed |
| EP-3153503-A1 | INTERMEDIATES FOR HALOGENOALKYLMETHYLENOXY-PHENYL-SUBSTITUTED KETOENOLS | Bayer Intellectual Property GmbH (DE) | 2017-04-12 | — | — | EP | disclosed |
| US-9045390-B2 | Haloalkylmethyleneoxyphenyl-substituted ketoenols | BAYER CROPSCIENCE AG (DE) | 2015-06-02 | — | — | US | disclosed |
| US-20140213813-A9 | Haloalkylmethyleneoxyphenyl-Substituted Ketoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-07-31 | — | — | US | disclosed |
| US-20140031577-A1 | Haloalkylmethyleneoxyphenyl-Substituted Ketoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-30 | — | — | US | disclosed |
| US-8518985-B2 | Haloalkylmethyleneoxyphenyl-substituted ketoenols | BAYER CROPSCIENCE AG (DE) | 2013-08-27 | — | — | US | disclosed |
| EP-2406216-A2 | HALOGENALKYLMETHYLENOXY-PHENYL-SUBSTITUTED KETOENOLS | Bayer Cropscience AG (DE) | 2012-01-18 | — | — | EP | disclosed |
| US-20100311593-A1 | Haloalkylmethyleneoxyphenyl-substituted ketoenols | BAYER CROPSCIENCE AG (DE) | 2010-12-09 | — | — | US | disclosed |
| WO-2010102758-A2 | HALOGENALKYLMETHYLENOXY-PHENYL-SUBSTITUTED KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2010-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213813-A9 | Haloalkylmethyleneoxyphenyl-Substituted Ketoenols | PHYKPL, KCNE1, CSNK1E | AGBL2 1432/4885RXRA 2712/4885RXRB 2859/4885 |
| US-20140031577-A1 | Haloalkylmethyleneoxyphenyl-Substituted Ketoenols | PHYKPL, KCNE1, CSNK1E | AGBL2 1432/4885RXRA 2712/4885RXRB 2859/4885 |
| US-20100311593-A1 | Haloalkylmethyleneoxyphenyl-substituted ketoenols | PHYKPL, KCNE1, CSNK1E | AGBL2 1432/4885RXRA 2712/4885RXRB 2859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.