Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1722174 | 0.84 | ALDH1A1 (0.39) | ALDH1A1TP53GAACYP2D6CYP2C19 | |
| SCHEMBL8708085 | 0.81 | POLB (0.40) | ALDH1A1TP53GAAMAPTPOLB | |
| SCHEMBL3174224 | 0.79 | TAS1R3 (0.35) | ALDH1A1TP53GAAMAPTTLR4 | |
| SCHEMBL8022828 | 0.79 | TP53 (0.39) | TP53POLBTAS1R3TAS1R1KDM4E | |
| SCHEMBL2431064 | 0.78 | MAPT (0.35) | ALDH1A1TP53GAAMAPTTLR4 | |
| SCHEMBL8703906 | 0.76 | POLB (0.39) | ALDH1A1GAAMAPTPOLBKDM4E | |
| SCHEMBL1720855 | 0.73 | AGBL2 (0.38) | CYP2C19MAPTPOLBTSHRKDM4E | |
| SCHEMBL14382020 | 0.73 | ATM (0.42) | ALDH1A1L3MBTL1MAPTTAS1R3TAS1R1 | |
| SCHEMBL3765142 | 0.72 | POLB (0.33) | POLBTSHR | |
| SCHEMBL2687043 | 0.72 | TAS1R3 (0.36) | ALDH1A1TP53GAACYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045390-B2 | Haloalkylmethyleneoxyphenyl-substituted ketoenols | BAYER CROPSCIENCE AG (DE) | 2015-06-02 | — | — | US | disclosed |
| US-20140213813-A9 | Haloalkylmethyleneoxyphenyl-Substituted Ketoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-07-31 | — | — | US | disclosed |
| US-20140031577-A1 | Haloalkylmethyleneoxyphenyl-Substituted Ketoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-30 | — | — | US | disclosed |
| US-8518985-B2 | Haloalkylmethyleneoxyphenyl-substituted ketoenols | BAYER CROPSCIENCE AG (DE) | 2013-08-27 | — | — | US | disclosed |
| US-20100311593-A1 | Haloalkylmethyleneoxyphenyl-substituted ketoenols | BAYER CROPSCIENCE AG (DE) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213813-A9 | Haloalkylmethyleneoxyphenyl-Substituted Ketoenols | PHYKPL, KCNE1, CSNK1E | ALDH1A1 4028/4885TP53 3600/4885GAA 392/4885 |
| US-20140031577-A1 | Haloalkylmethyleneoxyphenyl-Substituted Ketoenols | PHYKPL, KCNE1, CSNK1E | ALDH1A1 4028/4885TP53 3600/4885GAA 392/4885 |
| US-20100311593-A1 | Haloalkylmethyleneoxyphenyl-substituted ketoenols | PHYKPL, KCNE1, CSNK1E | ALDH1A1 4028/4885TP53 3600/4885GAA 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.