Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | GABRP | O00591 | 3/20 | 0.58 |
| ▸ | GABRD | O14764 | 3/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.58 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.58 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.58 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.58 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.58 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.58 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.58 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.58 |
| ▸ | GABRE | P78334 | 3/20 | 0.58 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.58 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.58 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.58 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL802769 | 0.87 | TRPV1 (0.63) | KMT2AALDH1A1HPGDNPSR1CYP1A2 | |
| N-Dihydroferuloyl Serotonin SCHEMBL10070990 | 0.82 | TRPV1 (0.61) | ALDH1A1HPGDNPSR1CYP1A2CYP3A4 | |
| SCHEMBL7023934 | 0.79 | LMNA (0.64) | KMT2AALDH1A1CYP2C9HPGDPMP22 | |
| SCHEMBL8168115 | 0.79 | ALDH1A1 (0.67) | KMT2AALDH1A1CYP2C9HPGDPMP22 | |
| SCHEMBL12720712 | 0.78 | SPR (0.58) | KMT2AALDH1A1CYP2C9HPGDPMP22 | |
| SCHEMBL27337415 | 0.76 | KMT2A (0.69) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7528872 | 0.75 | ERCC1 (0.73) | KMT2AALDH1A1CYP2C9HPGDPMP22 | |
| SCHEMBL7529264 | 0.75 | ERCC1 (0.73) | KMT2AALDH1A1CYP2C9HPGDPMP22 | |
| SCHEMBL20182374 | 0.75 | NPSR1 (0.68) | KMT2AALDH1A1CYP2C9HPGDPMP22 | |
| SCHEMBL853729 | 0.75 | NPSR1 (0.68) | KMT2AALDH1A1CYP2C9HPGDPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015162216-A1 | BIARYL AMIDE OR UREA DERIVATIVES AS TRPV1 LIGANDS | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2015-10-29 | — | — | WO | disclosed |