Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.68 |
| ▸ | GLA | P06280 | 1/20 | 0.68 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.59 |
| ▸ | SPR | P35270 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | BLM | P54132 | 2/20 | 0.59 |
| ▸ | IDO1 | P14902 | 1/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4473657 | 0.88 | HTR2C (0.54) | NPSR1ALDH1A1LMNACYP2C9TSHR | |
| SCHEMBL852680 | 0.86 | NPSR1 (0.64) | NPSR1ALDH1A1LMNACYP2C9TSHR | |
| SCHEMBL5177499 | 0.86 | PKM (0.68) | NPSR1ALDH1A1LMNACYP2C9TSHR | |
| SCHEMBL28006440 | 0.86 | NPSR1 (0.65) | NPSR1ALDH1A1LMNACYP2C9TSHR | |
| SCHEMBL2083266 | 0.85 | ALDH1A1 (0.51) | NPSR1ALDH1A1LMNACYP2C9TSHR | |
| SCHEMBL21255987 | 0.85 | MTNR1A (0.59) | NPSR1ALDH1A1LMNACYP2C9TSHR | |
| SCHEMBL2686551 | 0.84 | KDM4E (0.77) | ALDH1A1TSHRNFKB1HPGDPMP22 | |
| SCHEMBL20769666 | 0.84 | MTNR1A (0.60) | TSHRKDM4EIDO1KMT2AMEN1 | |
| SCHEMBL5817109 | 0.84 | KDM4E (0.53) | NPSR1ALDH1A1LMNACYP2C9TSHR | |
| SCHEMBL29444458 | 0.84 | MTNR1A (0.60) | NPSR1ALDH1A1LMNACYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12150447-B2 | Plant growth regulator | UNIVERSITY OF WASHINGTON (US) | 2024-11-26 | — | — | US | disclosed |
| US-12139459-B2 | Enhancer of fertilization function of sperm | TOHOKU UNIVERSITY (JP) | 2024-11-12 | — | — | US | disclosed |
| US-20240216524-A1 | Chemoselective Rapid Azo-Coupling Reaction for Bioconjugation | TRUSTEES BOSTON COLLEGE (US) | 2024-07-04 | — | — | US | disclosed |
| US-11890351-B2 | Chemoselective rapid azo-coupling reaction for bioconjugation | TRUSTEES OF BOSTON COLLEGE (US) | 2024-02-06 | — | — | US | disclosed |
| WO-2023028350-A1 | THERAPEUTIC COMPOSITIONS AND RELATED METHODS | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (US) | 2023-03-02 | — | — | WO | disclosed |
| US-20220106270-A1 | ENHANCER OF FERTILIZATION FUNCTION OF SPERM | KAKE EDUCATIONAL INSTITUTION (JP) | 2022-04-07 | — | — | US | disclosed |
| US-11147796-B2 | Agent for preventing or ameliorating hearing impairment | TOHOKU UNIVERSITY (JP) | 2021-10-19 | — | — | US | disclosed |
| US-11147796-B2 | Agent for preventing or ameliorating hearing impairment | TOHOKU UNIVERSITY (JP) | 2021-10-19 | — | — | US | disclosed |
| US-20210235697-A1 | PLANT GROWTH REGULATOR | UNIVERSITY OF WASHINGTON (US) | 2021-08-05 | — | — | US | disclosed |
| US-20210235697-A1 | PLANT GROWTH REGULATOR | UNIVERSITY OF WASHINGTON (US) | 2021-08-05 | — | — | US | disclosed |
| EP-1268422-A1 | INDOLES FOR TREATING DISEASES THAT CAN BE TREATED USING THYROID HORMONES | Bayer Aktiengesellschaft (DE) | 2003-01-02 | — | — | EP | disclosed |
| US-20020169200-A1 | Substituted indoles and their use as integrin antagonists | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2002-11-14 | — | — | US | disclosed |
| WO-2002060438-A1 | SUBSTITUTED INDOLES AND THEIR USE AS INTEGRIN ANTAGONISTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2002-08-08 | — | — | WO | disclosed |
| WO-2001070687-A1 | INDOLES FOR TREATING DISEASES THAT CAN BE TREATED USING THYROID HORMONES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-27 | — | — | WO | disclosed |
| EP-0548250-B1 | SUBSTITUTED BICYCLIC ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY | RHONE POULENC RORER INT (US) | 1996-03-27 | — | — | EP | disclosed |
| US-5468898-A | Substituted naphthylene compounds exhibiting selective leukotriene B4 antagonist activity | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1995-11-21 | — | — | US | disclosed |
| EP-0548250-A4 | SUBSTITUTED BICYCLIC ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B 4? ANTAGONIST ACTIVITY | — | 1993-10-27 | — | — | EP | disclosed |
| EP-0548250-A1 | SUBSTITUTED BICYCLIC ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B 4? ANTAGONIST ACTIVITY. | RHONE POULENC RORER INT (US) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992004321-A1 | SUBSTITUTED BICYCLIC ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-03-19 | — | — | WO | disclosed |
| EP-0252404-A2 | 5-Hydroxy-3-indoleacetic acid fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1988-01-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12139459-B2 | Enhancer of fertilization function of sperm | CATSPER1, NASP, ZP1 | NPSR1 906/4885ALDH1A1 2062/4885LMNA 3940/4885 |
| US-11147796-B2 | Agent for preventing or ameliorating hearing impairment | SLC26A4, OTC, SLC25A20 | NPSR1 2716/4885ALDH1A1 477/4885LMNA 2020/4885 |
| US-20240216524-A1 | Chemoselective Rapid Azo-Coupling Reaction for Bioconjugation | PAICS, DNPEP, ABCG2 | NPSR1 212/4885ALDH1A1 1482/4885LMNA 4623/4885 |
| US-20020169200-A1 | Substituted indoles and their use as integrin antagonists | ITGAV, ITGAL, ITGA5 | NPSR1 286/4885ALDH1A1 1662/4885LMNA 2941/4885 |
| US-20220106270-A1 | ENHANCER OF FERTILIZATION FUNCTION OF SPERM | CATSPER1, NASP, ZP1 | NPSR1 906/4885ALDH1A1 2062/4885LMNA 3940/4885 |
| US-20210235697-A1 | PLANT GROWTH REGULATOR | ING2, GHRHR, MYB | NPSR1 1066/4885ALDH1A1 3460/4885LMNA 4744/4885 |
| US-12150447-B2 | Plant growth regulator | ING2, GHRHR, MYB | NPSR1 1066/4885ALDH1A1 3460/4885LMNA 4744/4885 |
| US-11890351-B2 | Chemoselective rapid azo-coupling reaction for bioconjugation | PAICS, DNPEP, ABCG2 | NPSR1 212/4885ALDH1A1 1482/4885LMNA 4623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.