Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | SPR | P35270 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | IDO1 | P14902 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.59 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Dihydroferuloyl Serotonin SCHEMBL10070990 | 0.91 | TRPV1 (0.61) | TRPV1SPRKDM4ECYP1A2CYP3A4 | |
| SCHEMBL17209331 | 0.87 | KMT2A (0.70) | TRPV1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10084321 | 0.82 | SPR (0.63) | TRPV1SPRKDM4ECYP1A2CYP3A4 | |
| SCHEMBL14520190 | 0.80 | KMT2A (0.61) | MEN1KMT2ASPRKDM4ECYP1A2 | |
| N-Feruloyl Serotonin SCHEMBL30037765 | 0.80 | PTGS2 (0.79) | MEN1KMT2AACHE | |
| N-Feruloyl Serotonin SCHEMBL1809357 | 0.80 | PTGS2 (0.79) | MEN1KMT2AACHE | |
| N-Feruloyl Serotonin SCHEMBL12063415 | 0.80 | PTGS2 (0.79) | MEN1KMT2AACHE | |
| SCHEMBL1584079 | 0.80 | SPR (0.79) | TRPV1MEN1KMT2ASPRKDM4E | |
| SCHEMBL14703885 | 0.79 | CA1 (0.75) | ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL7513866 | 0.79 | KMT2A (0.88) | TRPV1MEN1KMT2AKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9295624-B2 | Amide derivative and whitening agent | AJINOMOTO CO., INC. (JP) | 2016-03-29 | — | — | US | disclosed |
| US-20140255327-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | AJINOMOTO CO. INC. (JP) | 2014-09-11 | — | — | US | disclosed |
| US-20130196050-A1 | SALTY TASTE ENHANCER | AJINOMOTO CO., INC. (JP) | 2013-08-01 | — | — | US | disclosed |
| US-20120070395-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | AJINOMOTO CO. INC (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130196050-A1 | SALTY TASTE ENHANCER | TAS2R10, TAS2R5, TAS1R1 | TRPV1 458/4885MEN1 2795/4885KMT2A 1560/4885 |
| US-20140255327-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | CUTA, NAT1, TYR | TRPV1 1051/4885MEN1 4229/4885KMT2A 644/4885 |
| US-20120070395-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | CUTA, NAT1, TYR | TRPV1 1051/4885MEN1 4229/4885KMT2A 644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.